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Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells.
Standoli S, Rapino C, Di Meo C, Rudowski A, Kämpfer-Kolb N, Volk LM, Thomas D, Trautmann S, Schreiber Y, Meyer Zu Heringdorf D, Maccarrone M. Standoli S, et al. Among authors: meyer zu heringdorf d. Int J Mol Sci. 2023 May 9;24(10):8508. doi: 10.3390/ijms24108508. Int J Mol Sci. 2023. PMID: 37239854 Free PMC article.
Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.
Vienken H, Mabrouki N, Grabau K, Claas RF, Rudowski A, Schömel N, Pfeilschifter J, Lütjohann D, van Echten-Deckert G, Meyer Zu Heringdorf D. Vienken H, et al. Among authors: meyer zu heringdorf d. Sci Rep. 2017 Mar 6;7:43575. doi: 10.1038/srep43575. Sci Rep. 2017. PMID: 28262793 Free PMC article.
Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells.
Blanchard O, Stepanovska B, Starck M, Erhardt M, Römer I, Meyer Zu Heringdorf D, Pfeilschifter J, Zangemeister-Wittke U, Huwiler A. Blanchard O, et al. Among authors: meyer zu heringdorf d. Int J Mol Sci. 2018 May 17;19(5):1498. doi: 10.3390/ijms19051498. Int J Mol Sci. 2018. PMID: 29772789 Free PMC article.
S1P d20:1, an endogenous modulator of S1P d18:1/S1P2 -dependent signaling.
Vutukuri R, Koch A, Trautmann S, Schreiber Y, Thomas D, Mayser F, Meyer Zu Heringdorf D, Pfeilschifter J, Pfeilschifter W, Brunkhorst R. Vutukuri R, et al. Among authors: meyer zu heringdorf d. FASEB J. 2020 Mar;34(3):3932-3942. doi: 10.1096/fj.201902391R. Epub 2020 Jan 15. FASEB J. 2020. PMID: 31944406
The WD40 repeat protein, WDR36, orchestrates sphingosine kinase-1 recruitment and phospholipase C-β activation by Gq-coupled receptors.
Blankenbach KV, Bruno G, Wondra E, Spohner AK, Aster NJ, Vienken H, Trautmann S, Ferreirós N, Wieland T, Bruni P, Meyer Zu Heringdorf D. Blankenbach KV, et al. Among authors: meyer zu heringdorf d. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158704. doi: 10.1016/j.bbalip.2020.158704. Epub 2020 Mar 31. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32244061
Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1.
Blankenbach KV, Claas RF, Aster NJ, Spohner AK, Trautmann S, Ferreirós N, Black JL, Tesmer JJG, Offermanns S, Wieland T, Meyer Zu Heringdorf D. Blankenbach KV, et al. Among authors: meyer zu heringdorf d. Cells. 2020 Sep 29;9(10):2201. doi: 10.3390/cells9102201. Cells. 2020. PMID: 33003441 Free PMC article.
The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection.
Imre G, Krähling V, Eichler M, Trautmann S, Ferreirós N, Aman MJ, Kashanchi F, Rajalingam K, Pöhlmann S, Becker S, Meyer Zu Heringdorf D, Pfeilschifter J. Imre G, et al. Among authors: meyer zu heringdorf d. iScience. 2021 Mar 5;24(4):102266. doi: 10.1016/j.isci.2021.102266. eCollection 2021 Apr 23. iScience. 2021. PMID: 33817572 Free PMC article.
Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile.
Spohner AK, Jakobi K, Trautmann S, Thomas D, Schumacher F, Kleuser B, Lütjohann D, El-Hindi K, Grösch S, Pfeilschifter J, Saba JD, Meyer Zu Heringdorf D. Spohner AK, et al. Among authors: meyer zu heringdorf d. Int J Mol Sci. 2021 Sep 30;22(19):10617. doi: 10.3390/ijms221910617. Int J Mol Sci. 2021. PMID: 34638955 Free PMC article.
55 results