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SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans.
Mudd PA, Minervina AA, Pogorelyy MV, Turner JS, Kim W, Kalaidina E, Petersen J, Schmitz AJ, Lei T, Haile A, Kirk AM, Mettelman RC, Crawford JC, Nguyen THO, Rowntree LC, Rosati E, Richards KA, Sant AJ, Klebert MK, Suessen T, Middleton WD; SJTRC Study Team; Wolf J, Teefey SA, O'Halloran JA, Presti RM, Kedzierska K, Rossjohn J, Thomas PG, Ellebedy AH. Mudd PA, et al. Among authors: mettelman rc. Cell. 2022 Feb 17;185(4):603-613.e15. doi: 10.1016/j.cell.2021.12.026. Epub 2021 Dec 23. Cell. 2022. PMID: 35026152 Free PMC article.
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response.
Lin CY, Wolf J, Brice DC, Sun Y, Locke M, Cherry S, Castellaw AH, Wehenkel M, Crawford JC, Zarnitsyna VI, Duque D, Allison KJ, Allen EK, Brown SA, Mandarano AH, Estepp JH; SJTRC Study Team; Taylor C, Molina-Paris C, Schultz-Cherry S, Tang L, Thomas PG, McGargill MA. Lin CY, et al. Cell Host Microbe. 2022 Jan 12;30(1):83-96.e4. doi: 10.1016/j.chom.2021.12.005. Epub 2021 Dec 7. Cell Host Microbe. 2022. PMID: 34965382 Free PMC article.
SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells.
Minervina AA, Pogorelyy MV, Kirk AM, Crawford JC, Allen EK, Chou CH, Mettelman RC, Allison KJ, Lin CY, Brice DC, Zhu X, Vegesana K, Wu G, Trivedi S, Kottapalli P, Darnell D, McNeely S, Olsen SR, Schultz-Cherry S, Estepp JH; SJTRC Study Team; McGargill MA, Wolf J, Thomas PG. Minervina AA, et al. Among authors: mettelman rc. Nat Immunol. 2022 May;23(5):781-790. doi: 10.1038/s41590-022-01184-4. Epub 2022 Apr 5. Nat Immunol. 2022. PMID: 35383307 Free PMC article.
Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages.
Wilson TL, Kim H, Chou CH, Langfitt D, Mettelman RC, Minervina AA, Allen EK, Métais JY, Pogorelyy MV, Riberdy JM, Velasquez MP, Kottapalli P, Trivedi S, Olsen SR, Lockey T, Willis C, Meagher MM, Triplett BM, Talleur AC, Gottschalk S, Crawford JC, Thomas PG. Wilson TL, et al. Among authors: mettelman rc. Cancer Discov. 2022 Sep 2;12(9):2098-2119. doi: 10.1158/2159-8290.CD-21-1508. Cancer Discov. 2022. PMID: 35792801 Free PMC article.
Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery.
Pogorelyy MV, Rosati E, Minervina AA, Mettelman RC, Scheffold A, Franke A, Bacher P, Thomas PG. Pogorelyy MV, et al. Among authors: mettelman rc. Cell Rep Med. 2022 Aug 16;3(8):100697. doi: 10.1016/j.xcrm.2022.100697. Epub 2022 Jul 1. Cell Rep Med. 2022. PMID: 35841887 Free PMC article.
Viral immunity: Basic mechanisms and therapeutic applications-a Keystone Symposia report.
Cable J, Balachandran S, Daley-Bauer LP, Rustagi A, Antony F, Frere JJ, Strampe J, Kedzierska K, Cannon JL, McGargill MA, Weiskopf D, Mettelman RC, Niessl J, Thomas PG, Briney B, Valkenburg SA, Bloom JD, Bjorkman PJ, Iketani S, Rappazzo CG, Crooks CM, Crofts KF, Pöhlmann S, Krammer F, Sant AJ, Nabel GJ, Schultz-Cherry S. Cable J, et al. Among authors: mettelman rc. Ann N Y Acad Sci. 2023 Mar;1521(1):32-45. doi: 10.1111/nyas.14960. Epub 2023 Jan 30. Ann N Y Acad Sci. 2023. PMID: 36718537
Baseline innate and T cell populations are correlates of protection against symptomatic influenza virus infection independent of serology.
Mettelman RC, Souquette A, Van de Velde LA, Vegesana K, Allen EK, Kackos CM, Trifkovic S, DeBeauchamp J, Wilson TL, St James DG, Menon SS, Wood T, Jelley L, Webby RJ, Huang QS, Thomas PG; SHIVERS-II Investigation Team. Mettelman RC, et al. Nat Immunol. 2023 Sep;24(9):1511-1526. doi: 10.1038/s41590-023-01590-2. Epub 2023 Aug 17. Nat Immunol. 2023. PMID: 37592015
21 results