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SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness.
bioRxiv [Preprint]. 2020 Jun 11:2020.06.11.145920. doi: 10.1101/2020.06.11.145920.
bioRxiv. 2020.
PMID: 32577634
Free PMC article.
Updated.
Preprint.
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.
Corbett KS, Edwards DK, Leist SR, Abiona OM, Boyoglu-Barnum S, Gillespie RA, Himansu S, Schäfer A, Ziwawo CT, DiPiazza AT, Dinnon KH, Elbashir SM, Shaw CA, Woods A, Fritch EJ, Martinez DR, Bock KW, Minai M, Nagata BM, Hutchinson GB, Wu K, Henry C, Bahl K, Garcia-Dominguez D, Ma L, Renzi I, Kong WP, Schmidt SD, Wang L, Zhang Y, Phung E, Chang LA, Loomis RJ, Altaras NE, Narayanan E, Metkar M, Presnyak V, Liu C, Louder MK, Shi W, Leung K, Yang ES, West A, Gully KL, Stevens LJ, Wang N, Wrapp D, Doria-Rose NA, Stewart-Jones G, Bennett H, Alvarado GS, Nason MC, Ruckwardt TJ, McLellan JS, Denison MR, Chappell JD, Moore IN, Morabito KM, Mascola JR, Baric RS, Carfi A, Graham BS.
Corbett KS, et al. Among authors: metkar m.
Nature. 2020 Oct;586(7830):567-571. doi: 10.1038/s41586-020-2622-0. Epub 2020 Aug 5.
Nature. 2020.
PMID: 32756549
Free PMC article.
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Tailor made: the art of therapeutic mRNA design.
Metkar M, Pepin CS, Moore MJ.
Metkar M, et al.
Nat Rev Drug Discov. 2024 Jan;23(1):67-83. doi: 10.1038/s41573-023-00827-x. Epub 2023 Nov 29.
Nat Rev Drug Discov. 2024.
PMID: 38030688
Review.
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Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved alternative splicing nonsense-mediated decay pathways.
Kovalak C, Donovan S, Bicknell AA, Metkar M, Moore MJ.
Kovalak C, et al. Among authors: metkar m.
Genome Biol. 2021 May 3;22(1):132. doi: 10.1186/s13059-021-02309-y.
Genome Biol. 2021.
PMID: 33941243
Free PMC article.
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Higher-Order Organization Principles of Pre-translational mRNPs.
Metkar M, Ozadam H, Lajoie BR, Imakaev M, Mirny LA, Dekker J, Moore MJ.
Metkar M, et al.
Mol Cell. 2018 Nov 15;72(4):715-726.e3. doi: 10.1016/j.molcel.2018.09.012. Epub 2018 Nov 8.
Mol Cell. 2018.
PMID: 30415953
Free PMC article.
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Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay.
Bicknell AA, Reid DW, Licata MC, Jones AK, Cheng YM, Li M, Hsiao CJ, Pepin CS, Metkar M, Levdansky Y, Fritz BR, Andrianova EA, Jain R, Valkov E, Köhrer C, Moore MJ.
Bicknell AA, et al. Among authors: metkar m.
Cell Rep. 2024 Apr 23;43(4):114098. doi: 10.1016/j.celrep.2024.114098. Epub 2024 Apr 15.
Cell Rep. 2024.
PMID: 38625793
Free article.
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