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HIV-1 IN inhibitors: 2010 update and perspectives.
Marchand C, Maddali K, Métifiot M, Pommier Y. Marchand C, et al. Among authors: metifiot m. Curr Top Med Chem. 2009;9(11):1016-37. doi: 10.2174/156802609789630910. Curr Top Med Chem. 2009. PMID: 19747122 Free PMC article. Review.
6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors.
Zhao XZ, Maddali K, Smith SJ, Métifiot M, Johnson BC, Marchand C, Hughes SH, Pommier Y, Burke TR Jr. Zhao XZ, et al. Among authors: metifiot m. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7309-13. doi: 10.1016/j.bmcl.2012.10.088. Epub 2012 Oct 27. Bioorg Med Chem Lett. 2012. PMID: 23149229 Free PMC article.
Bicyclic 1-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-containing HIV-1 integrase inhibitors having high antiviral potency against cells harboring raltegravir-resistant integrase mutants.
Zhao XZ, Smith SJ, Métifiot M, Johnson BC, Marchand C, Pommier Y, Hughes SH, Burke TR Jr. Zhao XZ, et al. Among authors: metifiot m. J Med Chem. 2014 Feb 27;57(4):1573-82. doi: 10.1021/jm401902n. Epub 2014 Feb 10. J Med Chem. 2014. PMID: 24471816 Free PMC article.
Basic quinolinonyl diketo acid derivatives as inhibitors of HIV integrase and their activity against RNase H function of reverse transcriptase.
Costi R, Métifiot M, Chung S, Cuzzucoli Crucitti G, Maddali K, Pescatori L, Messore A, Madia VN, Pupo G, Scipione L, Tortorella S, Di Leva FS, Cosconati S, Marinelli L, Novellino E, Le Grice SF, Corona A, Pommier Y, Marchand C, Di Santo R. Costi R, et al. Among authors: metifiot m. J Med Chem. 2014 Apr 24;57(8):3223-34. doi: 10.1021/jm5001503. Epub 2014 Apr 11. J Med Chem. 2014. PMID: 24684270 Free PMC article.
N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase.
Pescatori L, Métifiot M, Chung S, Masoaka T, Cuzzucoli Crucitti G, Messore A, Pupo G, Madia VN, Saccoliti F, Scipione L, Tortorella S, Di Leva FS, Cosconati S, Marinelli L, Novellino E, Le Grice SF, Pommier Y, Marchand C, Costi R, Di Santo R. Pescatori L, et al. Among authors: metifiot m. J Med Chem. 2015 Jun 11;58(11):4610-23. doi: 10.1021/acs.jmedchem.5b00159. Epub 2015 May 26. J Med Chem. 2015. PMID: 25961960 Free PMC article.
Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors.
Zhao XZ, Smith SJ, Maskell DP, Métifiot M, Pye VE, Fesen K, Marchand C, Pommier Y, Cherepanov P, Hughes SH, Burke TR Jr. Zhao XZ, et al. Among authors: metifiot m. J Med Chem. 2017 Sep 14;60(17):7315-7332. doi: 10.1021/acs.jmedchem.7b00596. Epub 2017 Aug 10. J Med Chem. 2017. PMID: 28737946 Free PMC article.
46 results