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Fructose stimulated de novo lipogenesis is promoted by inflammation.
Todoric J, Di Caro G, Reibe S, Henstridge DC, Green CR, Vrbanac A, Ceteci F, Conche C, McNulty R, Shalapour S, Taniguchi K, Meikle PJ, Watrous JD, Moranchel R, Najhawan M, Jain M, Liu X, Kisseleva T, Diaz-Meco MT, Moscat J, Knight R, Greten FR, Lau LF, Metallo CM, Febbraio MA, Karin M. Todoric J, et al. Among authors: metallo cm. Nat Metab. 2020 Oct;2(10):1034-1045. doi: 10.1038/s42255-020-0261-2. Epub 2020 Aug 24. Nat Metab. 2020. PMID: 32839596 Free PMC article.
EGFR + lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth.
Kuhlmann-Hogan A, Cordes T, Xu Z, Traina KA, Robles-Oteíza C, Ayeni D, Kwong EM, Levy SR, Nobari M, Cheng GZ, Shaw R, Leibel SL, Metallo CM, Politi K, Kaech SM. Kuhlmann-Hogan A, et al. Among authors: metallo cm. bioRxiv [Preprint]. 2023 Apr 17:2023.04.15.536974. doi: 10.1101/2023.04.15.536974. bioRxiv. 2023. PMID: 37131637 Free PMC article. Updated. Preprint.
Regulation of substrate utilization by the mitochondrial pyruvate carrier.
Vacanti NM, Divakaruni AS, Green CR, Parker SJ, Henry RR, Ciaraldi TP, Murphy AN, Metallo CM. Vacanti NM, et al. Among authors: metallo cm. Mol Cell. 2014 Nov 6;56(3):425-435. doi: 10.1016/j.molcel.2014.09.024. Epub 2014 Oct 30. Mol Cell. 2014. PMID: 25458843 Free PMC article.
Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues.
Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. Wallace M, et al. Among authors: metallo cm. Nat Chem Biol. 2018 Nov;14(11):1021-1031. doi: 10.1038/s41589-018-0132-2. Epub 2018 Oct 16. Nat Chem Biol. 2018. PMID: 30327559 Free PMC article.
Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.
Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, Scott DA, Metallo CM, Moscat J, Diaz-Meco MT. Reina-Campos M, et al. Among authors: metallo cm. Cancer Cell. 2019 Mar 18;35(3):385-400.e9. doi: 10.1016/j.ccell.2019.01.018. Epub 2019 Feb 28. Cancer Cell. 2019. PMID: 30827887 Free PMC article.
127 results