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Legacy data sharing to improve drug safety assessment: the eTOX project.
Sanz F, Pognan F, Steger-Hartmann T, Díaz C; eTOX; Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson DK, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes AJ, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I. Sanz F, et al. Among authors: mestres j. Nat Rev Drug Discov. 2017 Dec;16(12):811-812. doi: 10.1038/nrd.2017.177. Epub 2017 Oct 13. Nat Rev Drug Discov. 2017. PMID: 29026211 Free article.
Connecting small molecules to nuclear receptor pathways.
Hettne K, Cases M, Boyer S, Mestres J. Hettne K, et al. Among authors: mestres j. Curr Top Med Chem. 2007;7(15):1530-6. doi: 10.2174/156802607782194671. Curr Top Med Chem. 2007. PMID: 17897040
Shaping the future of safer innovative drugs in Europe.
Mestres J, Bryant SD, Zamora I, Gasteiger J. Mestres J, et al. Nat Biotechnol. 2011 Sep 8;29(9):789-90. doi: 10.1038/nbt.1973. Nat Biotechnol. 2011. PMID: 21904315 No abstract available.
Automatic filtering and substantiation of drug safety signals.
Bauer-Mehren A, van Mullingen EM, Avillach P, Carrascosa Mdel C, Garcia-Serna R, Piñero J, Singh B, Lopes P, Oliveira JL, Diallo G, Ahlberg Helgee E, Boyer S, Mestres J, Sanz F, Kors JA, Furlong LI. Bauer-Mehren A, et al. Among authors: mestres j. PLoS Comput Biol. 2012;8(4):e1002457. doi: 10.1371/journal.pcbi.1002457. Epub 2012 Apr 5. PLoS Comput Biol. 2012. PMID: 22496632 Free PMC article.
The EU-ADR Web Platform: delivering advanced pharmacovigilance tools.
Oliveira JL, Lopes P, Nunes T, Campos D, Boyer S, Ahlberg E, van Mulligen EM, Kors JA, Singh B, Furlong LI, Sanz F, Bauer-Mehren A, Carrascosa MC, Mestres J, Avillach P, Diallo G, Díaz Acedo C, van der Lei J. Oliveira JL, et al. Among authors: mestres j. Pharmacoepidemiol Drug Saf. 2013 May;22(5):459-67. doi: 10.1002/pds.3375. Epub 2012 Dec 4. Pharmacoepidemiol Drug Saf. 2013. PMID: 23208789
Scientific competency questions as the basis for semantically enriched open pharmacological space development.
Azzaoui K, Jacoby E, Senger S, Rodríguez EC, Loza M, Zdrazil B, Pinto M, Williams AJ, de la Torre V, Mestres J, Pastor M, Taboureau O, Rarey M, Chichester C, Pettifer S, Blomberg N, Harland L, Williams-Jones B, Ecker GF. Azzaoui K, et al. Among authors: mestres j. Drug Discov Today. 2013 Sep;18(17-18):843-52. doi: 10.1016/j.drudis.2013.05.008. Epub 2013 May 20. Drug Discov Today. 2013. PMID: 23702085 Free article. Review.
141 results