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Antitumoral effect of novel synthetic 8-hydroxy-2-((4-nitrophenyl)thio)naphthalene-1,4-dione (CNN16) via ROS-mediated DNA damage, apoptosis and anti-migratory effect in colon cancer cell line.
da Silva EL, Mesquita FP, Ramos INF, Gomes CBSMR, Moreira CDS, Ferreira VF, da Rocha DR, Bahia MO, Moreira-Nunes CA, de Souza CRT, Burbano RMR, Montenegro RC. da Silva EL, et al. Among authors: mesquita fp. Toxicol Appl Pharmacol. 2022 Dec 1;456:116256. doi: 10.1016/j.taap.2022.116256. Epub 2022 Oct 5. Toxicol Appl Pharmacol. 2022. PMID: 36208702
Small benzothiazole molecule induces apoptosis and prevents metastasis through DNA interaction and c-MYC gene supression in diffuse-type gastric adenocarcinoma cell line.
Mesquita FP, Pinto LC, Soares BM, de Sousa Portilho AJ, da Silva EL, de Farias Ramos IN, Khayat AS, Moreira-Nunes CA, Bezerra MM, de Lucas Chazin E, Vasconcelos TRA, Burbano RMR, de Moraes MEA, Montenegro RC. Mesquita FP, et al. Chem Biol Interact. 2018 Oct 1;294:118-127. doi: 10.1016/j.cbi.2018.08.006. Epub 2018 Aug 11. Chem Biol Interact. 2018. PMID: 30107152
Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib.
Montenegro RC, Howarth A, Ceroni A, Fedele V, Farran B, Mesquita FP, Frejno M, Berger BT, Heinzlmeir S, Sailem HZ, Tesch R, Ebner D, Knapp S, Burbano R, Kuster B, Müller S. Montenegro RC, et al. Among authors: mesquita fp. Oncotarget. 2020 Feb 4;11(5):535-549. doi: 10.18632/oncotarget.27462. eCollection 2020 Feb 4. Oncotarget. 2020. PMID: 32082487 Free PMC article.
22β-hydroxytingenone reduces proliferation and invasion of human melanoma cells.
Aranha ESP, da Silva EL, Mesquita FP, de Sousa LB, da Silva FMA, Rocha WC, Lima ES, Koolen HHF, de Moraes MEA, Montenegro RC, de Vasconcellos MC. Aranha ESP, et al. Among authors: mesquita fp. Toxicol In Vitro. 2020 Aug;66:104879. doi: 10.1016/j.tiv.2020.104879. Epub 2020 Apr 29. Toxicol In Vitro. 2020. PMID: 32360863 Free article.
22β-hydroxytingenone induces apoptosis and suppresses invasiveness of melanoma cells by inhibiting MMP-9 activity and MAPK signaling.
Aranha ESP, Portilho AJS, Bentes de Sousa L, da Silva EL, Mesquita FP, Rocha WC, Araújo da Silva FM, Lima ES, Alves APNN, Koolen HHF, Montenegro RC, Vasconcellos MC. Aranha ESP, et al. Among authors: mesquita fp. J Ethnopharmacol. 2021 Mar 1;267:113605. doi: 10.1016/j.jep.2020.113605. Epub 2020 Nov 21. J Ethnopharmacol. 2021. PMID: 33232779 Free article.
Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia.
Moreira-Nunes CA, Mesquita FP, Portilho AJS, Mello Júnior FAR, Maués JHDS, Pantoja LDC, Wanderley AV, Khayat AS, Zuercher WJ, Montenegro RC, de Moraes-Filho MO, de Moraes MEA. Moreira-Nunes CA, et al. Among authors: mesquita fp. Sci Rep. 2020 Dec 4;10(1):21272. doi: 10.1038/s41598-020-78024-8. Sci Rep. 2020. PMID: 33277547 Free PMC article.
49 results