Mertlíková-Kaiserová H - Search Results

1

Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.

Skácel J, Djukic S, Baszczyňski O, Kalčic F, Bílek T, Chalupský K, Kozák J, Dvořáková A, Tloušt'ová E, Král'ová Z, Šmídková M, Voldřich J, Rumlová M, Pachl P, Brynda J, Vučková T, Fábry M, Snášel J, Pichová I, Řezáčová P, Mertlíková-Kaiserová H, Janeba Z. Skácel J, et al. Among authors: mertlikova kaiserova h. J Med Chem. 2023 May 25;66(10):6652-6681. doi: 10.1021/acs.jmedchem.2c02097. Epub 2023 May 3. J Med Chem. 2023. PMID: 37134237 Free PMC article.

2

Point mutations in human guanylate kinase account for acquired resistance to anticancer nucleotide analogue PMEG.

Mertlíková-Kaiserová H, Rumlová M, Tloušťová E, Procházková E, Holý A, Votruba I. Mertlíková-Kaiserová H, et al. Biochem Pharmacol. 2011 Jul 15;82(2):131-8. doi: 10.1016/j.bcp.2011.04.002. Epub 2011 Apr 14. Biochem Pharmacol. 2011. PMID: 21515241 Free article.

3

2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential.

Matoušová M, Votruba I, Otmar M, Tloušťová E, Günterová J, Mertlíková-Kaiserová H. Matoušová M, et al. Epigenetics. 2011 Jun;6(6):769-76. doi: 10.4161/epi.6.6.16215. Epub 2011 Jun 1. Epigenetics. 2011. PMID: 21566456 Free PMC article.

4

SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors.

Sála M, De Palma AM, Hřebabecký H, Dejmek M, Dračínský M, Leyssen P, Neyts J, Mertlíková-Kaiserová H, Nencka R. Sála M, et al. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4271-5. doi: 10.1016/j.bmcl.2011.05.070. Epub 2011 May 27. Bioorg Med Chem Lett. 2011. PMID: 21684160

5

9-Norbornyl-6-chloropurine is a novel antileukemic compound interacting with cellular GSH.

Placková P, Rozumová N, Hrebabecky H, Sála M, Nencka R, Elbert T, Dvoráková A, Votruba I, Mertlíková-Kaiserová H. Placková P, et al. Anticancer Res. 2013 Aug;33(8):3163-8. Anticancer Res. 2013. PMID: 23898074

6

Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis.

Šmídková M, Dvoráková A, Tloust'ová E, Česnek M, Janeba Z, Mertlíková-Kaiserová H. Šmídková M, et al. Antimicrob Agents Chemother. 2014;58(2):664-71. doi: 10.1128/AAC.01685-13. Epub 2013 Oct 21. Antimicrob Agents Chemother. 2014. PMID: 24145524 Free PMC article.

7

Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.

Česnek M, Jansa P, Šmídková M, Mertlíková-Kaiserová H, Dračínský M, Brust TF, Pávek P, Trejtnar F, Watts VJ, Janeba Z. Česnek M, et al. ChemMedChem. 2015 Aug;10(8):1351-64. doi: 10.1002/cmdc.201500183. Epub 2015 Jul 1. ChemMedChem. 2015. PMID: 26136378

8

Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors.

Šála M, Kögler M, Plačková P, Mejdrová I, Hřebabecký H, Procházková E, Strunin D, Lee G, Birkus G, Weber J, Mertlíková-Kaiserová H, Nencka R. Šála M, et al. Bioorg Med Chem Lett. 2016 Jun 1;26(11):2706-12. doi: 10.1016/j.bmcl.2016.04.002. Epub 2016 Apr 5. Bioorg Med Chem Lett. 2016. PMID: 27090557 Free PMC article.

9

9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction.

Plačková P, Šála M, Šmídková M, Dejmek M, Hřebabecký H, Nencka R, Thibaut HJ, Neyts J, Mertlíková-Kaiserová H. Plačková P, et al. Free Radic Biol Med. 2016 Aug;97:223-235. doi: 10.1016/j.freeradbiomed.2016.06.004. Epub 2016 Jun 7. Free Radic Biol Med. 2016. PMID: 27288283 Free article.

10

Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.

Břehová P, Šmídková M, Skácel J, Dračínský M, Mertlíková-Kaiserová H, Velasquez MP, Watts VJ, Janeba Z. Břehová P, et al. ChemMedChem. 2016 Nov 21;11(22):2534-2546. doi: 10.1002/cmdc.201600439. Epub 2016 Oct 24. ChemMedChem. 2016. PMID: 27775243 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

42 results

Search Page