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The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection.
Marx AF, Kallert SM, Brunner TM, Villegas JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, Pinschewer DD. Marx AF, et al. Among authors: merkler d. Immunity. 2023 Apr 11;56(4):813-828.e10. doi: 10.1016/j.immuni.2023.01.029. Epub 2023 Feb 20. Immunity. 2023. PMID: 36809763 Free article.
Impaired antibody response causes persistence of prototypic T cell-contained virus.
Bergthaler A, Flatz L, Verschoor A, Hegazy AN, Holdener M, Fink K, Eschli B, Merkler D, Sommerstein R, Horvath E, Fernandez M, Fitsche A, Senn BM, Verbeek JS, Odermatt B, Siegrist CA, Pinschewer DD. Bergthaler A, et al. Among authors: merkler d. PLoS Biol. 2009 Apr 7;7(4):e1000080. doi: 10.1371/journal.pbio.1000080. PLoS Biol. 2009. PMID: 19355789 Free PMC article.
T cell-dependence of Lassa fever pathogenesis.
Flatz L, Rieger T, Merkler D, Bergthaler A, Regen T, Schedensack M, Bestmann L, Verschoor A, Kreutzfeldt M, Brück W, Hanisch UK, Günther S, Pinschewer DD. Flatz L, et al. Among authors: merkler d. PLoS Pathog. 2010 Mar 26;6(3):e1000836. doi: 10.1371/journal.ppat.1000836. PLoS Pathog. 2010. PMID: 20360949 Free PMC article.
Targeted ablation of oligodendrocytes triggers axonal damage.
Ghosh A, Manrique-Hoyos N, Voigt A, Schulz JB, Kreutzfeldt M, Merkler D, Simons M. Ghosh A, et al. Among authors: merkler d. PLoS One. 2011;6(7):e22735. doi: 10.1371/journal.pone.0022735. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818378 Free PMC article.
The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses.
Bonilla WV, Fröhlich A, Senn K, Kallert S, Fernandez M, Johnson S, Kreutzfeldt M, Hegazy AN, Schrick C, Fallon PG, Klemenz R, Nakae S, Adler H, Merkler D, Löhning M, Pinschewer DD. Bonilla WV, et al. Among authors: merkler d. Science. 2012 Feb 24;335(6071):984-9. doi: 10.1126/science.1215418. Epub 2012 Feb 9. Science. 2012. PMID: 22323740
253 results