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Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives.
Guillon J, Cohen A, Boudot C, Valle A, Milano V, Das RN, Guédin A, Moreau S, Ronga L, Savrimoutou S, Demourgues M, Reviriego E, Rubio S, Ferriez S, Agnamey P, Pauc C, Moukha S, Dozolme P, Nascimento SD, Laumaillé P, Bouchut A, Azas N, Mergny JL, Mullié C, Sonnet P, Courtioux B. Guillon J, et al. Among authors: mergny jl. J Enzyme Inhib Med Chem. 2020 Dec;35(1):432-459. doi: 10.1080/14756366.2019.1706502. J Enzyme Inhib Med Chem. 2020. PMID: 31899980 Free PMC article.
Sequence effects in single-base loops for quadruplexes.
Guédin A, De Cian A, Gros J, Lacroix L, Mergny JL. Guédin A, et al. Among authors: mergny jl. Biochimie. 2008 May;90(5):686-96. doi: 10.1016/j.biochi.2008.01.009. Epub 2008 Feb 2. Biochimie. 2008. PMID: 18294461
2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers.
El Bakali J, Klupsch F, Guédin A, Brassart B, Fontaine G, Farce A, Roussel P, Houssin R, Bernier JL, Chavatte P, Mergny JL, Riou JF, Hénichart JP. El Bakali J, et al. Among authors: mergny jl. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3434-8. doi: 10.1016/j.bmcl.2009.05.025. Epub 2009 May 12. Bioorg Med Chem Lett. 2009. PMID: 19473838
Exclusive platination of loop adenines in the human telomeric G-quadruplex.
Bertrand H, Bombard S, Monchaud D, Talbot E, Guédin A, Mergny JL, Grünert R, Bednarski PJ, Teulade-Fichou MP. Bertrand H, et al. Among authors: mergny jl. Org Biomol Chem. 2009 Jul 21;7(14):2864-71. doi: 10.1039/b904599f. Epub 2009 Jun 1. Org Biomol Chem. 2009. PMID: 19582295
Thermal melting studies of ligand DNA interactions.
Guédin A, Lacroix L, Mergny JL. Guédin A, et al. Among authors: mergny jl. Methods Mol Biol. 2010;613:25-35. doi: 10.1007/978-1-60327-418-0_2. Methods Mol Biol. 2010. PMID: 19997875
308 results