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Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Xu Z, Walker S, Wise MC, Chokkalingam N, Purwar M, Moore A, Tello-Ruiz E, Wu Y, Majumdar S, Konrath KM, Kulkarni A, Tursi NJ, Zaidi FI, Reuschel EL, Patel I, Obeirne A, Du J, Schultheis K, Gites L, Smith T, Mendoza J, Broderick KE, Humeau L, Pallesen J, Weiner DB, Kulp DW. Xu Z, et al. Among authors: mendoza j. Nat Commun. 2022 Feb 4;13(1):695. doi: 10.1038/s41467-022-28363-z. Nat Commun. 2022. PMID: 35121758 Free PMC article.
An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model.
Patel A, DiGiandomenico A, Keller AE, Smith TRF, Park DH, Ramos S, Schultheis K, Elliott STC, Mendoza J, Broderick KE, Wise MC, Yan J, Jiang J, Flingai S, Khan AS, Muthumani K, Humeau L, Cheng LI, Wachter-Rosati L, Stover CK, Sardesai NY, Weiner DB. Patel A, et al. Among authors: mendoza j. Nat Commun. 2017 Sep 21;8(1):637. doi: 10.1038/s41467-017-00576-7. Nat Commun. 2017. PMID: 28935938 Free PMC article.
In vivo delivery of synthetic DNA-encoded antibodies induces broad HIV-1-neutralizing activity.
Wise MC, Xu Z, Tello-Ruiz E, Beck C, Trautz A, Patel A, Elliott ST, Chokkalingam N, Kim S, Kerkau MG, Muthumani K, Jiang J, Fisher PD, Ramos SJ, Smith TR, Mendoza J, Broderick KE, Montefiori DC, Ferrari G, Kulp DW, Humeau LM, Weiner DB. Wise MC, et al. Among authors: mendoza j. J Clin Invest. 2020 Feb 3;130(2):827-837. doi: 10.1172/JCI132779. J Clin Invest. 2020. PMID: 31697648 Free PMC article.
HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo.
Muthumani K, Wise MC, Broderick KE, Hutnick N, Goodman J, Flingai S, Yan J, Bian CB, Mendoza J, Tingey C, Wilson C, Wojtak K, Sardesai NY, Weiner DB. Muthumani K, et al. Among authors: mendoza j. PLoS One. 2013 Dec 31;8(12):e84234. doi: 10.1371/journal.pone.0084234. eCollection 2013. PLoS One. 2013. PMID: 24391921 Free PMC article.
In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus.
Esquivel RN, Patel A, Kudchodkar SB, Park DH, Stettler K, Beltramello M, Allen JW, Mendoza J, Ramos S, Choi H, Borole P, Asija K, Bah M, Shaheen S, Chen J, Yan J, Durham AC, Smith TRF, Broderick K, Guibinga G, Muthumani K, Corti D, Humeau L, Weiner DB. Esquivel RN, et al. Among authors: mendoza j. Mol Ther. 2019 May 8;27(5):974-985. doi: 10.1016/j.ymthe.2019.03.005. Epub 2019 Apr 5. Mol Ther. 2019. PMID: 30962164 Free PMC article.
Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus.
Patel A, Reuschel EL, Xu Z, Zaidi FI, Kim KY, Scott DP, Mendoza J, Ramos S, Stoltz R, Feldmann F, Okumura A, Meade-White K, Haddock E, Thomas T, Rosenke R, Lovaglio J, Hanley PW, Saturday G, Muthumani K, Feldmann H, Humeau LM, Broderick KE, Weiner DB. Patel A, et al. Among authors: mendoza j. JCI Insight. 2021 May 24;6(10):e146082. doi: 10.1172/jci.insight.146082. JCI Insight. 2021. PMID: 33886507 Free PMC article.
Adipose tissue: a new target for electroporation-enhanced DNA vaccines.
Fisher PD, Brambila CJ, McCoy JR, Kiosses WB, Mendoza JM, Oh J, Yung BS, Schultheis K, Smith TRF, Broderick KE. Fisher PD, et al. Among authors: mendoza jm. Gene Ther. 2017 Dec;24(12):757-767. doi: 10.1038/gt.2017.96. Epub 2017 Nov 6. Gene Ther. 2017. PMID: 29106403 Free PMC article.
DMAb inoculation of synthetic cross reactive antibodies protects against lethal influenza A and B infections.
Elliott STC, Kallewaard NL, Benjamin E, Wachter-Rosati L, McAuliffe JM, Patel A, Smith TRF, Schultheis K, Park DH, Flingai S, Wise MC, Mendoza J, Ramos S, Broderick KE, Yan J, Humeau LM, Sardesai NY, Muthumani K, Zhu Q, Weiner DB. Elliott STC, et al. Among authors: mendoza j. NPJ Vaccines. 2017 Jul 6;2:18. doi: 10.1038/s41541-017-0020-x. eCollection 2017. NPJ Vaccines. 2017. PMID: 29263874 Free PMC article.
1,110 results