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New insights into thyroid hormone action.
Mendoza A, Hollenberg AN. Mendoza A, et al. Pharmacol Ther. 2017 May;173:135-145. doi: 10.1016/j.pharmthera.2017.02.012. Epub 2017 Feb 4. Pharmacol Ther. 2017. PMID: 28174093 Free PMC article. Review.
Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.
Mendoza A, Tang C, Choi J, Acuña M, Logan M, Martin AG, Al-Sowaimel L, Desai BN, Tenen DE, Jacobs C, Lyubetskaya A, Fu Y, Liu H, Tsai L, Cohen DE, Forrest D, Wilson AA, Hollenberg AN. Mendoza A, et al. Sci Signal. 2021 Nov 16;14(709):eabh3839. doi: 10.1126/scisignal.abh3839. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784250 Free PMC article.
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.
Liang N, Damdimopoulos A, Goñi S, Huang Z, Vedin LL, Jakobsson T, Giudici M, Ahmed O, Pedrelli M, Barilla S, Alzaid F, Mendoza A, Schröder T, Kuiper R, Parini P, Hollenberg A, Lefebvre P, Francque S, Van Gaal L, Staels B, Venteclef N, Treuter E, Fan R. Liang N, et al. Among authors: mendoza a. Nat Commun. 2019 Apr 11;10(1):1684. doi: 10.1038/s41467-019-09524-z. Nat Commun. 2019. PMID: 30975991 Free PMC article.
3,5-Diiodothyronine-mediated transrepression of the thyroid hormone receptor beta gene in tilapia. Insights on cross-talk between the thyroid hormone and cortisol signaling pathways.
Hernández-Puga G, Navarrete-Ramírez P, Mendoza A, Olvera A, Villalobos P, Orozco A. Hernández-Puga G, et al. Among authors: mendoza a. Mol Cell Endocrinol. 2016 Apr 15;425:103-10. doi: 10.1016/j.mce.2016.01.023. Epub 2016 Jan 26. Mol Cell Endocrinol. 2016. PMID: 26820127
3,5-T2 is an alternative ligand for the thyroid hormone receptor β1.
Mendoza A, Navarrete-Ramírez P, Hernández-Puga G, Villalobos P, Holzer G, Renaud JP, Laudet V, Orozco A. Mendoza A, et al. Endocrinology. 2013 Aug;154(8):2948-58. doi: 10.1210/en.2013-1030. Epub 2013 Jun 4. Endocrinology. 2013. PMID: 23736295
Enhancing standard of care chemotherapy efficacy using DNA-dependent protein kinase (DNA-PK) inhibition in preclinical models of Ewing sarcoma.
Collins VJ, Ludwig KR, Nelson AE, Sundara Rajan S, Yeung C, Vulikh K, Isanogle KA, Mendoza A, Difilippantonio S, Karim BO, Caplen NJ, Heske CM. Collins VJ, et al. Among authors: mendoza a. Mol Cancer Ther. 2024 Apr 24. doi: 10.1158/1535-7163.MCT-23-0641. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38657228
899 results