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Structure-activity studies of 7-heteroaryl-3-azabicyclo[3.3.1]non-6-enes: a novel class of highly potent nicotinic receptor ligands.
Breining SR, Melvin M, Bhatti BS, Byrd GD, Kiser MN, Hepler CD, Hooker DN, Zhang J, Reynolds LA, Benson LR, Fedorov NB, Sidach SS, Mitchener JP, Lucero LM, Lukas RJ, Whiteaker P, Yohannes D. Breining SR, et al. J Med Chem. 2012 Nov 26;55(22):9929-45. doi: 10.1021/jm3011299. Epub 2012 Oct 17. J Med Chem. 2012. PMID: 23025891
Pharmacological properties and predicted binding mode of arylmethylene quinuclidine-like derivatives at the α3β4 nicotinic acetylcholine receptor (nAChR).
Kombo DC, Hauser TA, Grinevich VP, Melvin MS, Strachan JP, Sidach SS, Chewning J, Fedorov N, Tallapragada K, Breining SR, Miller CH. Kombo DC, et al. Among authors: melvin ms. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1450-5. doi: 10.1016/j.bmcl.2012.12.054. Epub 2012 Dec 28. Bioorg Med Chem Lett. 2013. PMID: 23352509
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