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Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression.
Ruivo CF, Bastos N, Adem B, Batista I, Duraes C, Melo CA, Castaldo SA, Campos-Laborie F, Moutinho-Ribeiro P, Morão B, Costa-Pinto A, Silva S, Osorio H, Ciordia S, Costa JL, Goodrich D, Cavadas B, Pereira L, Kouzarides T, Macedo G, Maio R, Carneiro F, Cravo M, Kalluri R, Machado JC, Melo SA. Ruivo CF, et al. Among authors: melo ca. Gut. 2022 Jan 10;71(10):2043-68. doi: 10.1136/gutjnl-2021-324994. Online ahead of print. Gut. 2022. PMID: 35012996 Free PMC article.
MicroRNA biogenesis: dicing assay.
Melo CA, Melo SA. Melo CA, et al. Among authors: melo sa. Methods Mol Biol. 2014;1182:219-26. doi: 10.1007/978-1-4939-1062-5_20. Methods Mol Biol. 2014. PMID: 25055915
Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.
Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R. Melo SA, et al. Among authors: melo ca. Cancer Cell. 2014 Nov 10;26(5):707-21. doi: 10.1016/j.ccell.2014.09.005. Epub 2014 Oct 23. Cancer Cell. 2014. PMID: 25446899 Free PMC article.
eRNAs are required for p53-dependent enhancer activity and gene transcription.
Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. Melo CA, et al. Among authors: melo sa. Mol Cell. 2013 Feb 7;49(3):524-35. doi: 10.1016/j.molcel.2012.11.021. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273978 Free article.
Enhancer-associated RNAs as therapeutic targets.
Léveillé N, Melo CA, Agami R. Léveillé N, et al. Among authors: melo ca. Expert Opin Biol Ther. 2015 May;15(5):723-34. doi: 10.1517/14712598.2015.1029452. Epub 2015 Mar 29. Expert Opin Biol Ther. 2015. PMID: 25819025 Review.
Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity.
Léveillé N, Elkon R, Davalos V, Manoharan V, Hollingworth D, Oude Vrielink J, le Sage C, Melo CA, Horlings HM, Wesseling J, Ule J, Esteller M, Ramos A, Agami R. Léveillé N, et al. Among authors: melo ca. Nat Commun. 2011 Oct 25;2:513. doi: 10.1038/ncomms1519. Nat Commun. 2011. PMID: 22027593 Free PMC article.
eRNAs reach the heart of transcription.
Melo CA, Léveillé N, Agami R. Melo CA, et al. Cell Res. 2013 Oct;23(10):1151-2. doi: 10.1038/cr.2013.97. Epub 2013 Jul 23. Cell Res. 2013. PMID: 23877407 Free PMC article.
65 results