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Harnessing IgG Fc glycosylation for clinical benefit.
Archer EJ, Gonzalez JC, Ghosh D, Mellins ED, Wang TT. Archer EJ, et al. Among authors: mellins ed. Curr Opin Immunol. 2022 Aug;77:102231. doi: 10.1016/j.coi.2022.102231. Epub 2022 Jul 4. Curr Opin Immunol. 2022. PMID: 35797920 Free PMC article. Review.
Accessory molecules for MHC class II peptide loading.
Busch R, Doebele RC, Patil NS, Pashine A, Mellins ED. Busch R, et al. Among authors: mellins ed. Curr Opin Immunol. 2000 Feb;12(1):99-106. doi: 10.1016/s0952-7915(99)00057-6. Curr Opin Immunol. 2000. PMID: 10679402 Review.
The MHC class II cofactor HLA-DM interacts with Ig in B cells.
Macmillan H, Strohman MJ, Ayyangar S, Jiang W, Rajasekaran N, Spura A, Hessell AJ, Madec AM, Mellins ED. Macmillan H, et al. Among authors: mellins ed. J Immunol. 2014 Sep 15;193(6):2641-2650. doi: 10.4049/jimmunol.1400075. Epub 2014 Aug 6. J Immunol. 2014. PMID: 25098292 Free PMC article.
New insights into B cells as antigen presenting cells.
Ghosh D, Jiang W, Mukhopadhyay D, Mellins ED. Ghosh D, et al. Among authors: mellins ed. Curr Opin Immunol. 2021 Jun;70:129-137. doi: 10.1016/j.coi.2021.06.003. Epub 2021 Jul 6. Curr Opin Immunol. 2021. PMID: 34242927 Review.
Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles.
Saper VE, Ombrello MJ, Tremoulet AH, Montero-Martin G, Prahalad S, Canna S, Shimizu C, Deutsch G, Tan SY, Remmers EF, Monos D, Hahn T, Phadke OK, Cassidy E, Ferguson I, Mallajosyula V, Xu J, Rosa Duque JS, Chua GT, Ghosh D, Szymanski AM, Rubin D, Burns JC, Tian L, Fernandez-Vina MA, Mellins ED, Hollenbach JA; Drug Hypersensitivity Consortium; INCHARGE Consortium. Saper VE, et al. Among authors: mellins ed. Ann Rheum Dis. 2022 Mar;81(3):406-415. doi: 10.1136/annrheumdis-2021-220578. Epub 2021 Nov 17. Ann Rheum Dis. 2022. PMID: 34789453 Free PMC article.
Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity.
Chakraborty S, Gonzalez JC, Sievers BL, Mallajosyula V, Chakraborty S, Dubey M, Ashraf U, Cheng BY, Kathale N, Tran KQT, Scallan C, Sinnott A, Cassidy A, Chen ST, Gelbart T, Gao F, Golan Y, Ji X, Kim-Schulze S, Prahl M, Gaw SL, Gnjatic S, Marron TU, Merad M, Arunachalam PS, Boyd SD, Davis MM, Holubar M, Khosla C, Maecker HT, Maldonado Y, Mellins ED, Nadeau KC, Pulendran B, Singh U, Subramanian A, Utz PJ, Sherwood R, Zhang S, Jagannathan P, Tan GS, Wang TT. Chakraborty S, et al. Among authors: mellins ed. Sci Transl Med. 2022 Mar 9;14(635):eabm7853. doi: 10.1126/scitranslmed.abm7853. Epub 2022 Mar 9. Sci Transl Med. 2022. PMID: 35040666 Free PMC article.
Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells.
Ghosh D, Pham TD, Nanaware PP, Sengupta D, Adler LN, Li CG, He X, O'Mara ME, Kantor AB, Nguyen KD, Yang Y, Eisenlohr LC, Jensen PE, Herzenberg LA, Stern LJ, Boyd SD, Ghosn EEB, Mellins ED. Ghosh D, et al. Among authors: mellins ed. Cell Rep. 2022 Jan 25;38(4):110200. doi: 10.1016/j.celrep.2021.110200. Cell Rep. 2022. PMID: 35081339 Free article.
181 results