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Maintenance of Primary Human Colorectal Cancer Microenvironment Using a Perfusion Bioreactor-Based 3D Culture System.
Manfredonia C, Muraro MG, Hirt C, Mele V, Governa V, Papadimitropoulos A, Däster S, Soysal SD, Droeser RA, Mechera R, Oertli D, Rosso R, Bolli M, Zettl A, Terracciano LM, Spagnoli GC, Martin I, Iezzi G. Manfredonia C, et al. Among authors: mele v. Adv Biosyst. 2019 Apr;3(4):e1800300. doi: 10.1002/adbi.201800300. Epub 2019 Mar 7. Adv Biosyst. 2019. PMID: 32627426
"In vitro" 3D models of tumor-immune system interaction.
Hirt C, Papadimitropoulos A, Mele V, Muraro MG, Mengus C, Iezzi G, Terracciano L, Martin I, Spagnoli GC. Hirt C, et al. Among authors: mele v. Adv Drug Deliv Rev. 2014 Dec 15;79-80:145-54. doi: 10.1016/j.addr.2014.05.003. Epub 2014 May 9. Adv Drug Deliv Rev. 2014. PMID: 24819215 Review.
Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo".
Hirt C, Papadimitropoulos A, Muraro MG, Mele V, Panopoulos E, Cremonesi E, Ivanek R, Schultz-Thater E, Droeser RA, Mengus C, Heberer M, Oertli D, Iezzi G, Zajac P, Eppenberger-Castori S, Tornillo L, Terracciano L, Martin I, Spagnoli GC. Hirt C, et al. Among authors: mele v. Biomaterials. 2015 Sep;62:138-46. doi: 10.1016/j.biomaterials.2015.05.037. Epub 2015 May 20. Biomaterials. 2015. PMID: 26051518
Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β.
Mele V, Muraro MG, Calabrese D, Pfaff D, Amatruda N, Amicarella F, Kvinlaug B, Bocelli-Tyndall C, Martin I, Resink TJ, Heberer M, Oertli D, Terracciano L, Spagnoli GC, Iezzi G. Mele V, et al. Int J Cancer. 2014 Jun 1;134(11):2583-94. doi: 10.1002/ijc.28598. Epub 2014 Jan 30. Int J Cancer. 2014. PMID: 24214914 Free PMC article.
Absence of myeloperoxidase and CD8 positive cells in colorectal cancer infiltrates identifies patients with severe prognosis.
Däster S, Eppenberger-Castori S, Hirt C, Soysal SD, Delko T, Nebiker CA, Weixler B, Amicarella F, Iezzi G, Governa V, Padovan E, Mele V, Sconocchia G, Heberer M, Terracciano L, Kettelhack C, Oertli D, Spagnoli GC, von Holzen U, Tornillo L, Droeser RA. Däster S, et al. Among authors: mele v. Oncoimmunology. 2015 May 29;4(12):e1050574. doi: 10.1080/2162402X.2015.1050574. eCollection 2015 Dec. Oncoimmunology. 2015. PMID: 26587320 Free PMC article.
The Interplay Between Neutrophils and CD8+ T Cells Improves Survival in Human Colorectal Cancer.
Governa V, Trella E, Mele V, Tornillo L, Amicarella F, Cremonesi E, Muraro MG, Xu H, Droeser R, Däster SR, Bolli M, Rosso R, Oertli D, Eppenberger-Castori S, Terracciano LM, Iezzi G, Spagnoli GC. Governa V, et al. Among authors: mele v. Clin Cancer Res. 2017 Jul 15;23(14):3847-3858. doi: 10.1158/1078-0432.CCR-16-2047. Epub 2017 Jan 20. Clin Cancer Res. 2017. PMID: 28108544
Gut microbiota modulate T cell trafficking into human colorectal cancer.
Cremonesi E, Governa V, Garzon JFG, Mele V, Amicarella F, Muraro MG, Trella E, Galati-Fournier V, Oertli D, Däster SR, Droeser RA, Weixler B, Bolli M, Rosso R, Nitsche U, Khanna N, Egli A, Keck S, Slotta-Huspenina J, Terracciano LM, Zajac P, Spagnoli GC, Eppenberger-Castori S, Janssen KP, Borsig L, Iezzi G. Cremonesi E, et al. Among authors: mele v. Gut. 2018 Nov;67(11):1984-1994. doi: 10.1136/gutjnl-2016-313498. Epub 2018 Feb 6. Gut. 2018. PMID: 29437871 Free article.
73 results