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Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques.
Borggren M, Vinner L, Andresen BS, Grevstad B, Repits J, Melchers M, Elvang TL, Sanders RW, Martinon F, Dereuddre-Bosquet N, Bowles EJ, Stewart-Jones G, Biswas P, Scarlatti G, Jansson M, Heyndrickx L, Grand RL, Fomsgaard A. Borggren M, et al. Among authors: melchers m. Vaccines (Basel). 2013 Jul 19;1(3):305-27. doi: 10.3390/vaccines1030305. Vaccines (Basel). 2013. PMID: 26344115 Free PMC article.
Antibodies to HIV-1: aiming at the right target.
Eggink D, Melchers M, Sanders RW. Eggink D, et al. Among authors: melchers m. Trends Microbiol. 2007 Jul;15(7):291-4. doi: 10.1016/j.tim.2007.05.006. Epub 2007 Jun 12. Trends Microbiol. 2007. PMID: 17566740
A chimeric HIV-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF) domain induces enhanced antibody and T cell responses.
van Montfort T, Melchers M, Isik G, Menis S, Huang PS, Matthews K, Michael E, Berkhout B, Schief WR, Moore JP, Sanders RW. van Montfort T, et al. Among authors: melchers m. J Biol Chem. 2011 Jun 24;286(25):22250-61. doi: 10.1074/jbc.M111.229625. Epub 2011 Apr 22. J Biol Chem. 2011. PMID: 21515681 Free PMC article.
Immunosilencing a highly immunogenic protein trimerization domain.
Sliepen K, van Montfort T, Melchers M, Isik G, Sanders RW. Sliepen K, et al. Among authors: melchers m. J Biol Chem. 2015 Mar 20;290(12):7436-42. doi: 10.1074/jbc.M114.620534. Epub 2015 Jan 29. J Biol Chem. 2015. PMID: 25635058 Free PMC article.
55 results