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Enhancing the Drug-Like Profile of a Potent Peptide PACE4 Inhibitor by the Formation of a Host-Guest Inclusion Complex with β-Cyclodextrin.
Mol Pharm. 2023 Sep 4;20(9):4559-4573. doi: 10.1021/acs.molpharmaceut.3c00261. Epub 2023 Aug 9.
Mol Pharm. 2023.
PMID: 37555521
Efficacy of PACE4 pharmacotherapy in JHU-LNCaP-SM preclinical model of androgen independent prostate cancer.
Mekdad N, Tran TMH, Desjardins R, Kwiatkowska A, Couture F, Day R.
Mekdad N, et al.
Sci Rep. 2022 Oct 19;12(1):17489. doi: 10.1038/s41598-022-21593-7.
Sci Rep. 2022.
PMID: 36261691
Free PMC article.
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Individual differences in cocaine-induced conditioned place preference in male rats: Behavioral and transcriptomic evidence.
Atehortua Martinez LA, Curis E, Mekdad N, Larrieu C, Courtin C, Jourdren L, Blugeon C, Laplanche JL, Megarbane B, Marie-Claire C, Benturquia N.
Atehortua Martinez LA, et al. Among authors: mekdad n.
J Psychopharmacol. 2022 Oct;36(10):1161-1175. doi: 10.1177/02698811221123047. Epub 2022 Sep 19.
J Psychopharmacol. 2022.
PMID: 36121009
Free PMC article.
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Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances.
Vorspan F, Icick R, Mekdad N, Courtin C, Bloch V, Bellivier F, Laplanche JL, Prince N, Pishalin D, Firmo C, Blugeon C, Mégarbane B, Marie-Claire C, Benturquia N.
Vorspan F, et al. Among authors: mekdad n.
Transl Psychiatry. 2020 Nov 6;10(1):381. doi: 10.1038/s41398-020-01050-7.
Transl Psychiatry. 2020.
PMID: 33159041
Free PMC article.
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