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Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.
Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, Leite AC. Moreira DR, et al. Among authors: meira cs. J Med Chem. 2012 Dec 27;55(24):10918-36. doi: 10.1021/jm301518v. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23167554
Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB. Moreira DR, et al. Among authors: meira cs. ChemMedChem. 2014 Jan;9(1):177-88. doi: 10.1002/cmdc.201300354. Epub 2013 Nov 7. ChemMedChem. 2014. PMID: 24203393
Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death.
Bastos TM, Barbosa MI, da Silva MM, da C Júnior JW, Meira CS, Guimaraes ET, Ellena J, Moreira DR, Batista AA, Soares MB. Bastos TM, et al. Among authors: meira cs. Antimicrob Agents Chemother. 2014 Oct;58(10):6044-55. doi: 10.1128/AAC.02765-14. Epub 2014 Aug 4. Antimicrob Agents Chemother. 2014. PMID: 25092707 Free PMC article.
65 results