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Page 1
Fructose stimulated de novo lipogenesis is promoted by inflammation.
Todoric J, Di Caro G, Reibe S, Henstridge DC, Green CR, Vrbanac A, Ceteci F, Conche C, McNulty R, Shalapour S, Taniguchi K, Meikle PJ, Watrous JD, Moranchel R, Najhawan M, Jain M, Liu X, Kisseleva T, Diaz-Meco MT, Moscat J, Knight R, Greten FR, Lau LF, Metallo CM, Febbraio MA, Karin M. Todoric J, et al. Among authors: meikle pj. Nat Metab. 2020 Oct;2(10):1034-1045. doi: 10.1038/s42255-020-0261-2. Epub 2020 Aug 24. Nat Metab. 2020. PMID: 32839596 Free PMC article.
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance.
Matthews VB, Allen TL, Risis S, Chan MH, Henstridge DC, Watson N, Zaffino LA, Babb JR, Boon J, Meikle PJ, Jowett JB, Watt MJ, Jansson JO, Bruce CR, Febbraio MA. Matthews VB, et al. Among authors: meikle pj. Diabetologia. 2010 Nov;53(11):2431-41. doi: 10.1007/s00125-010-1865-y. Epub 2010 Aug 11. Diabetologia. 2010. PMID: 20697689
Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice.
Henstridge DC, Bruce CR, Pang CP, Lancaster GI, Allen TL, Estevez E, Gardner T, Weir JM, Meikle PJ, Lam KSL, Xu A, Fujii N, Goodyear LJ, Febbraio MA. Henstridge DC, et al. Among authors: meikle pj. Diabetologia. 2012 Oct;55(10):2769-2778. doi: 10.1007/s00125-012-2652-8. Epub 2012 Jul 26. Diabetologia. 2012. PMID: 22832498 Free PMC article.
Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding.
Turner N, Kowalski GM, Leslie SJ, Risis S, Yang C, Lee-Young RS, Babb JR, Meikle PJ, Lancaster GI, Henstridge DC, White PJ, Kraegen EW, Marette A, Cooney GJ, Febbraio MA, Bruce CR. Turner N, et al. Among authors: meikle pj. Diabetologia. 2013 Jul;56(7):1638-48. doi: 10.1007/s00125-013-2913-1. Epub 2013 Apr 26. Diabetologia. 2013. PMID: 23620060
The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice.
Sapra G, Tham YK, Cemerlang N, Matsumoto A, Kiriazis H, Bernardo BC, Henstridge DC, Ooi JY, Pretorius L, Boey EJ, Lim L, Sadoshima J, Meikle PJ, Mellet NA, Woodcock EA, Marasco S, Ueyama T, Du XJ, Febbraio MA, McMullen JR. Sapra G, et al. Among authors: meikle pj. Nat Commun. 2014 Dec 9;5:5705. doi: 10.1038/ncomms6705. Nat Commun. 2014. PMID: 25489988 Free article.
Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.
Henstridge DC, Estevez E, Allen TL, Heywood SE, Gardner T, Yang C, Mellett NA, Kingwell BA, Meikle PJ, Febbraio MA. Henstridge DC, et al. Among authors: meikle pj. Cell Stress Chaperones. 2015 May;20(3):461-72. doi: 10.1007/s12192-015-0571-6. Epub 2015 Jan 25. Cell Stress Chaperones. 2015. PMID: 25618331 Free PMC article.
Analysis of the liver lipidome reveals insights into the protective effect of exercise on high-fat diet-induced hepatosteatosis in mice.
Jordy AB, Kraakman MJ, Gardner T, Estevez E, Kammoun HL, Weir JM, Kiens B, Meikle PJ, Febbraio MA, Henstridge DC. Jordy AB, et al. Among authors: meikle pj. Am J Physiol Endocrinol Metab. 2015 May 1;308(9):E778-91. doi: 10.1152/ajpendo.00547.2014. Epub 2015 Feb 24. Am J Physiol Endocrinol Metab. 2015. PMID: 25714675 Free article.
321 results