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Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias.
González-Martínez J, Cwetsch AW, Martínez-Alonso D, López-Sainz LR, Almagro J, Melati A, Gómez J, Pérez-Martínez M, Megías D, Boskovic J, Gilabert-Juan J, Graña-Castro O, Pierani A, Behrens A, Ortega S, Malumbres M. González-Martínez J, et al. Among authors: megias d. JCI Insight. 2021 Aug 23;6(16):e146364. doi: 10.1172/jci.insight.146364. JCI Insight. 2021. PMID: 34237032 Free PMC article.
A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis.
Pérez de Castro I, Aguirre-Portolés C, Martin B, Fernández-Miranda G, Klotzbucher A, Kubbutat MH, Megías D, Arlot-Bonnemains Y, Malumbres M. Pérez de Castro I, et al. Among authors: megias d. Front Oncol. 2011 Dec 14;1:50. doi: 10.3389/fonc.2011.00050. eCollection 2011. Front Oncol. 2011. PMID: 22649767 Free PMC article.
Reprogramming in vivo produces teratomas and iPS cells with totipotency features.
Abad M, Mosteiro L, Pantoja C, Cañamero M, Rayon T, Ors I, Graña O, Megías D, Domínguez O, Martínez D, Manzanares M, Ortega S, Serrano M. Abad M, et al. Among authors: megias d. Nature. 2013 Oct 17;502(7471):340-5. doi: 10.1038/nature12586. Epub 2013 Sep 11. Nature. 2013. PMID: 24025773
Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia.
Piazzolla D, Palla AR, Pantoja C, Cañamero M, de Castro IP, Ortega S, Gómez-López G, Dominguez O, Megías D, Roncador G, Luque-Garcia JL, Fernandez-Tresguerres B, Fernandez AF, Fraga MF, Rodriguez-Justo M, Manzanares M, Sánchez-Carbayo M, García-Pedrero JM, Rodrigo JP, Malumbres M, Serrano M. Piazzolla D, et al. Among authors: megias d. Nat Commun. 2014 Jun 30;5:4226. doi: 10.1038/ncomms5226. Nat Commun. 2014. PMID: 24979572 Free article.
AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest.
Doménech E, Maestre C, Esteban-Martínez L, Partida D, Pascual R, Fernández-Miranda G, Seco E, Campos-Olivas R, Pérez M, Megias D, Allen K, López M, Saha AK, Velasco G, Rial E, Méndez R, Boya P, Salazar-Roa M, Malumbres M. Doménech E, et al. Among authors: megias d. Nat Cell Biol. 2015 Oct;17(10):1304-16. doi: 10.1038/ncb3231. Epub 2015 Aug 31. Nat Cell Biol. 2015. PMID: 26322680
In Vivo DNA Re-replication Elicits Lethal Tissue Dysplasias.
Muñoz S, Búa S, Rodríguez-Acebes S, Megías D, Ortega S, de Martino A, Méndez J. Muñoz S, et al. Among authors: megias d. Cell Rep. 2017 May 2;19(5):928-938. doi: 10.1016/j.celrep.2017.04.032. Cell Rep. 2017. PMID: 28467906 Free article.
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