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The HLA-B*57:01 allele corresponds to a very large MHC haploblock likely explaining its massive effect for HIV-1 elite control.
Rahmouni M, De Marco L, Spadoni JL, Tison M, Medina-Santos R, Labib T, Noirel J, Tamouza R, Limou S, Delaneau O, Fellay J, Bensussan A, Le Clerc S, McLaren PJ, Zagury JF. Rahmouni M, et al. Among authors: medina santos r. Front Immunol. 2023 Dec 11;14:1305856. doi: 10.3389/fimmu.2023.1305856. eCollection 2023. Front Immunol. 2023. PMID: 38146367 Free PMC article.
Analysis of NGS data from Peruvian Loxosceles laeta spider venom gland reveals toxin diversity.
Medina-Santos R, Fernandes Costa TG, Silva de Assis TC, Kalapothakis Y, de Almeida Lima S, do Carmo AO, Gonzalez-Kozlova EE, Kalapothakis E, Chávez-Olórtegui C, Guerra-Duarte C. Medina-Santos R, et al. Comp Biochem Physiol Part D Genomics Proteomics. 2022 Sep;43:101017. doi: 10.1016/j.cbd.2022.101017. Epub 2022 Jul 30. Comp Biochem Physiol Part D Genomics Proteomics. 2022. PMID: 35932519 Review.
Immunoprotection against lethal effects of Crotalus durissus snake venom elicited by synthetic epitopes trapped in liposomes.
D Vaz de Melo P, de Almeida Lima S, Araújo P, Medina Santos R, Gonzalez E, Alves Belo A, Machado-de-Ávila RA, Costal-Oliveira F, T Soccol V, Guerra-Duarte C, Rezende L, Chavez-Olortegui C. D Vaz de Melo P, et al. Among authors: medina santos r. Int J Biol Macromol. 2020 Oct 15;161:299-307. doi: 10.1016/j.ijbiomac.2020.05.171. Epub 2020 May 25. Int J Biol Macromol. 2020. PMID: 32464201
Diversity of astacin-like metalloproteases identified by transcriptomic analysis in Peruvian Loxosceles laeta spider venom and in vitro activity characterization.
Medina-Santos R, Guerra-Duarte C, de Almeida Lima S, Costal-Oliveira F, Alves de Aquino P, Oliveira do Carmo A, Ferreyra CB, Gonzalez-Kozlova EE, Kalapothakis E, Chávez-Olórtegui C. Medina-Santos R, et al. Biochimie. 2019 Dec;167:81-92. doi: 10.1016/j.biochi.2019.08.017. Epub 2019 Aug 30. Biochimie. 2019. PMID: 31476328