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Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy.
Ghzaiel I, Zarrouk A, Essadek S, Martine L, Hammouda S, Yammine A, Ksila M, Nury T, Meddeb W, Tahri Joutey M, Mihoubi W, Caccia C, Leoni V, Samadi M, Acar N, Andreoletti P, Hammami S, Ghrairi T, Vejux A, Hammami M, Lizard G. Ghzaiel I, et al. Among authors: meddeb w. Steroids. 2022 Jul;183:109032. doi: 10.1016/j.steroids.2022.109032. Epub 2022 Apr 4. Steroids. 2022. PMID: 35381271
Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells.
Debbabi M, Zarrouk A, Bezine M, Meddeb W, Nury T, Badreddine A, Karym EM, Sghaier R, Bretillon L, Guyot S, Samadi M, Cherkaoui-Malki M, Nasser B, Mejri M, Ben-Hammou S, Hammami M, Lizard G. Debbabi M, et al. Among authors: meddeb w. Chem Phys Lipids. 2017 Oct;207(Pt B):151-170. doi: 10.1016/j.chemphyslip.2017.04.002. Epub 2017 Apr 10. Chem Phys Lipids. 2017. PMID: 28408132
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N.
Badreddine A, Zarrouk A, Karym EM, Debbabi M, Nury T, Meddeb W, Sghaier R, Bezine M, Vejux A, Martine L, Grégoire S, Bretillon L, Prost-Camus E, Durand P, Prost M, Moreau T, Cherkaoui-Malki M, Nasser B, Lizard G. Badreddine A, et al. Among authors: meddeb w. Int J Mol Sci. 2017 Oct 23;18(10):2220. doi: 10.3390/ijms18102220. Int J Mol Sci. 2017. PMID: 29065513 Free PMC article.
Prevention of 7-ketocholesterol-induced side effects by natural compounds.
Brahmi F, Vejux A, Sghaier R, Zarrouk A, Nury T, Meddeb W, Rezig L, Namsi A, Sassi K, Yammine A, Badreddine I, Vervandier-Fasseur D, Madani K, Boulekbache-Makhlouf L, Nasser B, Lizard G. Brahmi F, et al. Among authors: meddeb w. Crit Rev Food Sci Nutr. 2019;59(19):3179-3198. doi: 10.1080/10408398.2018.1491828. Epub 2018 Oct 16. Crit Rev Food Sci Nutr. 2019. PMID: 29993272 Review.
Profile of Fatty Acids, Tocopherols, Phytosterols and Polyphenols in Mediterranean Oils (Argan Oils, Olive Oils, Milk Thistle Seed Oils and Nigella Seed Oil) and Evaluation of their Antioxidant and Cytoprotective Activities.
Zarrouk A, Martine L, Grégoire S, Nury T, Meddeb W, Camus E, Badreddine A, Durand P, Namsi A, Yammine A, Nasser B, Mejri M, Bretillon L, Mackrill JJ, Cherkaoui-Malki M, Hammami M, Lizard G. Zarrouk A, et al. Among authors: meddeb w. Curr Pharm Des. 2019;25(15):1791-1805. doi: 10.2174/1381612825666190705192902. Curr Pharm Des. 2019. PMID: 31298157
In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy.
Ghzaiel I, Maaloul S, Ksila M, Namsi A, Yammine A, Debbabi M, Badreddine A, Meddeb W, Pires V, Nury T, Ménétrier F, Avoscan L, Zarrouk A, Baarine M, Masmoudi-Kouki O, Ghrairi T, Abdellaoui R, Nasser B, Hammami S, Hammami M, Samadi M, Vejux A, Lizard G. Ghzaiel I, et al. Among authors: meddeb w. Adv Exp Med Biol. 2024;1440:437-452. doi: 10.1007/978-3-031-43883-7_21. Adv Exp Med Biol. 2024. PMID: 38036892