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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Cobo-Vuilleumier N, Lorenzo PI, Rodríguez NG, Herrera Gómez IG, Fuente-Martin E, López-Noriega L, Mellado-Gil JM, Romero-Zerbo SY, Baquié M, Lachaud CC, Stifter K, Perdomo G, Bugliani M, De Tata V, Bosco D, Parnaud G, Pozo D, Hmadcha A, Florido JP, Toscano MG, de Haan P, Schoonjans K, Sánchez Palazón L, Marchetti P, Schirmbeck R, Martín-Montalvo A, Meda P, Soria B, Bermúdez-Silva FJ, St-Onge L, Gauthier BR. Cobo-Vuilleumier N, et al. Among authors: meda p. Nat Commun. 2018 Apr 16;9(1):1488. doi: 10.1038/s41467-018-03943-0. Nat Commun. 2018. PMID: 29662071 Free PMC article.
PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.
Mellado-Gil JM, Jiménez-Moreno CM, Martin-Montalvo A, Alvarez-Mercado AI, Fuente-Martin E, Cobo-Vuilleumier N, Lorenzo PI, Bru-Tari E, Herrera-Gómez Ide G, López-Noriega L, Pérez-Florido J, Santoyo-López J, Spyrantis A, Meda P, Boehm BO, Quesada I, Gauthier BR. Mellado-Gil JM, et al. Among authors: meda p. Diabetologia. 2016 Apr;59(4):755-65. doi: 10.1007/s00125-016-3864-0. Epub 2016 Jan 26. Diabetologia. 2016. PMID: 26813254 Free PMC article.
Reconstructing islet function in vitro.
Bosco D, Meda P. Bosco D, et al. Among authors: meda p. Adv Exp Med Biol. 1997;426:285-98. doi: 10.1007/978-1-4899-1819-2_39. Adv Exp Med Biol. 1997. PMID: 9544286 Review. No abstract available.
Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.
Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P. Serre-Beinier V, et al. Among authors: meda p. Hum Mol Genet. 2009 Feb 1;18(3):428-39. doi: 10.1093/hmg/ddn370. Epub 2008 Nov 10. Hum Mol Genet. 2009. PMID: 19000992 Free PMC article.
Connexins: key mediators of endocrine function.
Bosco D, Haefliger JA, Meda P. Bosco D, et al. Among authors: meda p. Physiol Rev. 2011 Oct;91(4):1393-445. doi: 10.1152/physrev.00027.2010. Physiol Rev. 2011. PMID: 22013215 Free article. Review.
300 results