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Metformin treatment rescues CD8+ T-cell response to immune checkpoint inhibitor therapy in mice with NAFLD.
Wabitsch S, McCallen JD, Kamenyeva O, Ruf B, McVey JC, Kabat J, Walz JS, Rotman Y, Bauer KC, Craig AJ, Pouzolles M, Phadke I, Catania V, Green BL, Fu C, Diggs LP, Heinrich B, Wang XW, Ma C, Greten TF. Wabitsch S, et al. Among authors: mcvey jc. J Hepatol. 2022 Sep;77(3):748-760. doi: 10.1016/j.jhep.2022.03.010. Epub 2022 Apr 1. J Hepatol. 2022. PMID: 35378172 Free PMC article.
Steatohepatitis Impairs T-cell-Directed Immunotherapies Against Liver Tumors in Mice.
Heinrich B, Brown ZJ, Diggs LP, Vormehr M, Ma C, Subramanyam V, Rosato U, Ruf B, Walz JS, McVey JC, Wabitsch S, Fu Q, Yu SJ, Zhang Q, Lai CW, Sahin U, Greten TF. Heinrich B, et al. Among authors: mcvey jc. Gastroenterology. 2021 Jan;160(1):331-345.e6. doi: 10.1053/j.gastro.2020.09.031. Epub 2020 Oct 1. Gastroenterology. 2021. PMID: 33010248 Free PMC article.
CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma.
Diggs LP, Ruf B, Ma C, Heinrich B, Cui L, Zhang Q, McVey JC, Wabitsch S, Heinrich S, Rosato U, Lai W, Subramanyam V, Longerich T, Loosen SH, Luedde T, Neumann UP, Desar S, Kleiner D, Gores G, Wang XW, Greten TF. Diggs LP, et al. Among authors: mcvey jc. J Hepatol. 2021 May;74(5):1145-1154. doi: 10.1016/j.jhep.2020.11.037. Epub 2020 Dec 1. J Hepatol. 2021. PMID: 33276030 Free PMC article.
Anti-PD-1 in Combination With Trametinib Suppresses Tumor Growth and Improves Survival of Intrahepatic Cholangiocarcinoma in Mice.
Wabitsch S, Tandon M, Ruf B, Zhang Q, McCallen JD, McVey JC, Ma C, Green BL, Diggs LP, Heinrich B, Greten TF. Wabitsch S, et al. Among authors: mcvey jc. Cell Mol Gastroenterol Hepatol. 2021;12(3):1166-1178. doi: 10.1016/j.jcmgh.2021.05.011. Epub 2021 May 23. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34033968 Free PMC article.
The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma.
Heinrich B, Gertz EM, Schäffer AA, Craig A, Ruf B, Subramanyam V, McVey JC, Diggs LP, Heinrich S, Rosato U, Ma C, Yan C, Hu Y, Zhao Y, Shen TW, Kapoor V, Telford W, Kleiner DE, Stovroff MK, Dhani HS, Kang J, Fishbein T, Wang XW, Ruppin E, Kroemer A, Greten TF, Korangy F. Heinrich B, et al. Among authors: mcvey jc. Gut. 2022 Jun;71(6):1161-1175. doi: 10.1136/gutjnl-2021-325288. Epub 2021 Aug 2. Gut. 2022. PMID: 34340996 Free PMC article.
Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD.
Ma C, Fu Q, Diggs LP, McVey JC, McCallen J, Wabitsch S, Ruf B, Brown Z, Heinrich B, Zhang Q, Rosato U, Wang S, Cui L, Berzofsky JA, Kleiner DE, Bosco DB, Wu LJ, Lai CW, Rotman Y, Xie C, Korangy F, Greten TF. Ma C, et al. Among authors: mcvey jc. Cancer Cell. 2022 Sep 12;40(9):986-998.e5. doi: 10.1016/j.ccell.2022.08.004. Epub 2022 Sep 1. Cancer Cell. 2022. PMID: 36055226 Free PMC article.
24 results