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Hypomorphic GINS3 variants alter DNA replication and cause Meier-Gorlin syndrome.
McQuaid ME, Ahmed K, Tran S, Rousseau J, Shaheen R, Kernohan KD, Yuki KE, Grover P, Dreseris ES, Ahmed S, Dupuis L, Stimec J, Shago M, Al-Hassnan ZN, Tremblay R, Maass PG, Wilson MD, Grunebaum E, Boycott KM, Boisvert FM, Maddirevula S, Faqeih EA, Almanjomi F, Khan ZU, Alkuraya FS, Campeau PM, Kannu P, Campos EI, Wurtele H. McQuaid ME, et al. JCI Insight. 2022 May 23;7(10):e155648. doi: 10.1172/jci.insight.155648. JCI Insight. 2022. PMID: 35603789 Free PMC article.
Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells.
Benslimane Y, Bertomeu T, Coulombe-Huntington J, McQuaid M, Sánchez-Osuna M, Papadopoli D, Avizonis D, Russo MST, Huard C, Topisirovic I, Wurtele H, Tyers M, Harrington L. Benslimane Y, et al. Mol Cell. 2020 Sep 3;79(5):846-856.e8. doi: 10.1016/j.molcel.2020.07.010. Epub 2020 Aug 4. Mol Cell. 2020. PMID: 32755594 Free article.
An open-source algorithm for rapid unbiased determination of DNA fiber length.
Ghesquière P, Elsherbiny A, Fortier E, McQuaid M, Mazzaferri J, Bélanger F, Cheriet F, Drobetsky E, Wurtele H, Costantino S. Ghesquière P, et al. DNA Repair (Amst). 2019 Feb;74:26-37. doi: 10.1016/j.dnarep.2019.01.003. Epub 2019 Jan 11. DNA Repair (Amst). 2019. PMID: 30665830