McNeil M - Search Results

1

MmpL3 inhibitors as antituberculosis drugs.

Shao M, McNeil M, Cook GM, Lu X. Shao M, et al. Among authors: mcneil m. Eur J Med Chem. 2020 Aug 15;200:112390. doi: 10.1016/j.ejmech.2020.112390. Epub 2020 May 4. Eur J Med Chem. 2020. PMID: 32447196 Review.

2

The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria.

McNeil MB, Hampton HG, Hards KJ, Watson BN, Cook GM, Fineran PC. McNeil MB, et al. FEBS Lett. 2014 Jan 31;588(3):414-21. doi: 10.1016/j.febslet.2013.12.019. Epub 2013 Dec 25. FEBS Lett. 2014. PMID: 24374335 Free article.

3

Utilization of CRISPR Interference To Validate MmpL3 as a Drug Target in Mycobacterium tuberculosis.

McNeil MB, Cook GM. McNeil MB, et al. Antimicrob Agents Chemother. 2019 Jul 25;63(8):e00629-19. doi: 10.1128/AAC.00629-19. Print 2019 Aug. Antimicrob Agents Chemother. 2019. PMID: 31160289 Free PMC article.

4

Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents.

Hards K, Adolph C, Harold LK, McNeil MB, Cheung CY, Jinich A, Rhee KY, Cook GM. Hards K, et al. Among authors: mcneil mb. Prog Biophys Mol Biol. 2020 May;152:35-44. doi: 10.1016/j.pbiomolbio.2019.11.003. Epub 2019 Nov 13. Prog Biophys Mol Biol. 2020. PMID: 31733221 Review.

5

Transcriptional Inhibition of the F₁F₀-Type ATP Synthase Has Bactericidal Consequences on the Viability of Mycobacteria.

McNeil MB, Ryburn HWK, Harold LK, Tirados JF, Cook GM. McNeil MB, et al. Antimicrob Agents Chemother. 2020 Jul 22;64(8):e00492-20. doi: 10.1128/AAC.00492-20. Print 2020 Jul 22. Antimicrob Agents Chemother. 2020. PMID: 32423951 Free PMC article.

6

Multiple Mutations in Mycobacterium tuberculosis MmpL3 Increase Resistance to MmpL3 Inhibitors.

McNeil MB, O'Malley T, Dennison D, Shelton CD, Sunde B, Parish T. McNeil MB, et al. mSphere. 2020 Oct 14;5(5):e00985-20. doi: 10.1128/mSphere.00985-20. mSphere. 2020. PMID: 33055263 Free PMC article.

7

CRISPR interference identifies vulnerable cellular pathways with bactericidal phenotypes in Mycobacterium tuberculosis.

McNeil MB, Keighley LM, Cook JR, Cheung CY, Cook GM. McNeil MB, et al. Mol Microbiol. 2021 Oct;116(4):1033-1043. doi: 10.1111/mmi.14790. Epub 2021 Aug 21. Mol Microbiol. 2021. PMID: 34346123 Free article.

8

Utilization of CRISPR interference to investigate the contribution of genes to pathogenesis in a macrophage model of Mycobacterium tuberculosis infection.

Cheung CY, McNeil MB, Cook GM. Cheung CY, et al. Among authors: mcneil mb. J Antimicrob Chemother. 2022 Feb 23;77(3):615-619. doi: 10.1093/jac/dkab437. J Antimicrob Chemother. 2022. PMID: 34850009

9

Multiplexed transcriptional repression identifies a network of bactericidal interactions between mycobacterial respiratory complexes.

McNeil MB, Ryburn HW, Tirados J, Cheung CY, Cook GM. McNeil MB, et al. iScience. 2021 Dec 4;25(1):103573. doi: 10.1016/j.isci.2021.103573. eCollection 2022 Jan 21. iScience. 2021. PMID: 34984329 Free PMC article.

10

An amiloride derivative is active against the F₁F_o-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis.

Hards K, Cheung CY, Waller N, Adolph C, Keighley L, Tee ZS, Harold LK, Menorca A, Bujaroski RS, Buckley BJ, Tyndall JDA, McNeil MB, Rhee KY, Opel-Reading HK, Krause K, Preiss L, Langer JD, Meier T, Hasenoehrl EJ, Berney M, Kelso MJ, Cook GM. Hards K, et al. Among authors: mcneil mb. Commun Biol. 2022 Feb 24;5(1):166. doi: 10.1038/s42003-022-03110-8. Commun Biol. 2022. PMID: 35210534 Free PMC article.

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