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A year-long extended release nanoformulated cabotegravir prodrug.
Kulkarni TA, Bade AN, Sillman B, Shetty BLD, Wojtkiewicz MS, Gautam N, Hilaire JR, Sravanam S, Szlachetka A, Lamberty BG, Morsey BM, Fox HS, Alnouti Y, McMillan JM, Mosley RL, Meza J, Domanico PL, Yue TY, Moore G, Edagwa BJ, Gendelman HE. Kulkarni TA, et al. Among authors: mcmillan jm. Nat Mater. 2020 Aug;19(8):910-920. doi: 10.1038/s41563-020-0674-z. Epub 2020 Apr 27. Nat Mater. 2020. PMID: 32341511 Free PMC article.
Creation of a Long-Acting Nanoformulated 2',3'-Dideoxy-3'-Thiacytidine.
Guo D, Zhou T, Araínga M, Palandri D, Gautam N, Bronich T, Alnouti Y, McMillan J, Edagwa B, Gendelman HE. Guo D, et al. J Acquir Immune Defic Syndr. 2017 Mar 1;74(3):e75-e83. doi: 10.1097/QAI.0000000000001170. J Acquir Immune Defic Syndr. 2017. PMID: 27559685 Free PMC article.
Long-acting slow effective release antiretroviral therapy.
Edagwa B, McMillan J, Sillman B, Gendelman HE. Edagwa B, et al. Expert Opin Drug Deliv. 2017 Nov;14(11):1281-1291. doi: 10.1080/17425247.2017.1288212. Epub 2017 Feb 6. Expert Opin Drug Deliv. 2017. PMID: 28128004 Free PMC article. Review.
Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles.
Zhou T, Su H, Dash P, Lin Z, Dyavar Shetty BL, Kocher T, Szlachetka A, Lamberty B, Fox HS, Poluektova L, Gorantla S, McMillan J, Gautam N, Mosley RL, Alnouti Y, Edagwa B, Gendelman HE. Zhou T, et al. Biomaterials. 2018 Jan;151:53-65. doi: 10.1016/j.biomaterials.2017.10.023. Epub 2017 Oct 15. Biomaterials. 2018. PMID: 29059541 Free PMC article.
Creation of a long-acting nanoformulated dolutegravir.
Sillman B, Bade AN, Dash PK, Bhargavan B, Kocher T, Mathews S, Su H, Kanmogne GD, Poluektova LY, Gorantla S, McMillan J, Gautam N, Alnouti Y, Edagwa B, Gendelman HE. Sillman B, et al. Nat Commun. 2018 Feb 6;9(1):443. doi: 10.1038/s41467-018-02885-x. Nat Commun. 2018. PMID: 29402886 Free PMC article.
Synthesis of a long acting nanoformulated emtricitabine ProTide.
Soni D, Bade AN, Gautam N, Herskovitz J, Ibrahim IM, Smith N, Wojtkiewicz MS, Dyavar Shetty BL, Alnouti Y, McMillan J, Gendelman HE, Edagwa BJ. Soni D, et al. Biomaterials. 2019 Nov;222:119441. doi: 10.1016/j.biomaterials.2019.119441. Epub 2019 Aug 20. Biomaterials. 2019. PMID: 31472458 Free PMC article.
A long acting nanoformulated lamivudine ProTide.
Smith N, Bade AN, Soni D, Gautam N, Alnouti Y, Herskovitz J, Ibrahim IM, Wojtkiewicz MS, Dyavar Shetty BL, McMillan J, Gendelman HE, Edagwa B. Smith N, et al. Biomaterials. 2019 Dec;223:119476. doi: 10.1016/j.biomaterials.2019.119476. Epub 2019 Sep 5. Biomaterials. 2019. PMID: 31525692 Free PMC article.
142 results