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HDAC Inhibition Regulates Cardiac Function by Increasing Myofilament Calcium Sensitivity and Decreasing Diastolic Tension.
Eaton DM, Martin TG, Kasa M, Djalinac N, Ljubojevic-Holzer S, Von Lewinski D, Pöttler M, Kampaengsri T, Krumphuber A, Scharer K, Maechler H, Zirlik A, McKinsey TA, Kirk JA, Houser SR, Rainer PP, Wallner M. Eaton DM, et al. Among authors: mckinsey ta. Pharmaceutics. 2022 Jul 21;14(7):1509. doi: 10.3390/pharmaceutics14071509. Pharmaceutics. 2022. PMID: 35890404 Free PMC article.
HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR. Wallner M, et al. Among authors: mckinsey ta. Sci Transl Med. 2020 Jan 8;12(525):eaay7205. doi: 10.1126/scitranslmed.aay7205. Sci Transl Med. 2020. PMID: 31915304 Free PMC article.
Cardiac Remodeling During Pregnancy With Metabolic Syndrome: Prologue of Pathological Remodeling.
Yang Y, Kurian J, Schena G, Johnson J, Kubo H, Travers JG, Kang C, Lucchese AM, Eaton DM, Lv M, Li N, Leynes LG, Yu D, Yang F, McKinsey TA, Kishore R, Khan M, Mohsin S, Houser SR. Yang Y, et al. Among authors: mckinsey ta. Circulation. 2021 Feb 16;143(7):699-712. doi: 10.1161/CIRCULATIONAHA.120.051264. Epub 2021 Feb 15. Circulation. 2021. PMID: 33587660 Free PMC article.
HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Travers JG, Wennersten SA, Peña B, Bagchi RA, Smith HE, Hirsch RA, Vanderlinden LA, Lin YH, Dobrinskikh E, Demos-Davies KM, Cavasin MA, Mestroni L, Steinkühler C, Lin CY, Houser SR, Woulfe KC, Lam MPY, McKinsey TA. Travers JG, et al. Among authors: mckinsey ta. Circulation. 2021 May 11;143(19):1874-1890. doi: 10.1161/CIRCULATIONAHA.120.046462. Epub 2021 Mar 8. Circulation. 2021. PMID: 33682427 Free PMC article.
Cortical bone stem cells modify cardiac inflammation after myocardial infarction by inducing a novel macrophage phenotype.
Hobby ARH, Berretta RM, Eaton DM, Kubo H, Feldsott E, Yang Y, Headrick AL, Koch KA, Rubino M, Kurian J, Khan M, Tan Y, Mohsin S, Gallucci S, McKinsey TA, Houser SR. Hobby ARH, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2021 Oct 1;321(4):H684-H701. doi: 10.1152/ajpheart.00304.2021. Epub 2021 Aug 20. Am J Physiol Heart Circ Physiol. 2021. PMID: 34415185 Free PMC article.
Cortical bone stem cell-derived exosomes' therapeutic effect on myocardial ischemia-reperfusion and cardiac remodeling.
Schena GJ, Murray EK, Hildebrand AN, Headrick AL, Yang Y, Koch KA, Kubo H, Eaton D, Johnson J, Berretta R, Mohsin S, Kishore R, McKinsey TA, Elrod JW, Houser SR. Schena GJ, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2021 Dec 1;321(6):H1014-H1029. doi: 10.1152/ajpheart.00197.2021. Epub 2021 Oct 8. Am J Physiol Heart Circ Physiol. 2021. PMID: 34623184 Free PMC article.
Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF.
Eaton DM, Berretta RM, Lynch JE, Travers JG, Pfeiffer RD, Hulke ML, Zhao H, Hobby ARH, Schena G, Johnson JP, Wallner M, Lau E, Lam MPY, Woulfe KC, Tucker NR, McKinsey TA, Wolfson MR, Houser SR. Eaton DM, et al. Among authors: mckinsey ta. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H797-H817. doi: 10.1152/ajpheart.00374.2022. Epub 2022 Sep 2. Am J Physiol Heart Circ Physiol. 2022. PMID: 36053749 Free PMC article.
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Jeong MY, et al. Among authors: mckinsey ta. Sci Transl Med. 2018 Feb 7;10(427):eaao0144. doi: 10.1126/scitranslmed.aao0144. Sci Transl Med. 2018. PMID: 29437146 Free PMC article.
183 results