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Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression.
Wang L, Warzecha CC, Kistner A, Chichester JA, Bell P, Buza EL, He Z, Pampena MB, Couthouis J, Sethi S, McKeever K, Betts MR, Kakkis E, Wilson JM, Wadsworth S, Sullivan BA. Wang L, et al. Among authors: mckeever k. Mol Ther Methods Clin Dev. 2022 Jan 19;24:292-305. doi: 10.1016/j.omtm.2022.01.007. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35211641 Free PMC article.
Safety and tolerability of an anti-CD19 monoclonal antibody, MEDI-551, in subjects with systemic sclerosis: a phase I, randomized, placebo-controlled, escalating single-dose study.
Schiopu E, Chatterjee S, Hsu V, Flor A, Cimbora D, Patra K, Yao W, Li J, Streicher K, McKeever K, White B, Katz E, Drappa J, Sweeny S, Herbst R. Schiopu E, et al. Among authors: mckeever k. Arthritis Res Ther. 2016 Jun 7;18(1):131. doi: 10.1186/s13075-016-1021-2. Arthritis Res Ther. 2016. PMID: 27267753 Free PMC article. Clinical Trial.
Effects of ICOS+ T cell depletion via afucosylated monoclonal antibody MEDI-570 on pregnant cynomolgus monkeys and the developing offspring.
Nicholson SM, Carlesso G, Cheng LI, Cook H, DaCosta K, Leininger J, McKeever K, Scott SW, Taylor D, Streicher K, Eck S, Reed M, Faggioni R, Herbst R, Dixit R, Ryan PC. Nicholson SM, et al. Among authors: mckeever k. Reprod Toxicol. 2017 Dec;74:116-133. doi: 10.1016/j.reprotox.2017.08.018. Epub 2017 Sep 13. Reprod Toxicol. 2017. PMID: 28916434
Pharmacokinetic and Pharmacodynamic Modeling to Optimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment of Patients with Mucopolysaccharidosis Type VII: Results from Three Trials.
Qi Y, McKeever K, Taylor J, Haller C, Song W, Jones SA, Shi J. Qi Y, et al. Among authors: mckeever k. Clin Pharmacokinet. 2019 May;58(5):673-683. doi: 10.1007/s40262-018-0721-y. Clin Pharmacokinet. 2019. PMID: 30467742 Free PMC article. Clinical Trial.
150 results