McInnes LE - Search Results

1

Bifunctional (64)Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography.

Paterson BM, Buncic G, McInnes LE, Roselt P, Cullinane C, Binns DS, Jeffery CM, Price RI, Hicks RJ, Donnelly PS. Paterson BM, et al. Among authors: mcinnes le. Dalton Trans. 2015 Mar 21;44(11):4901-9. doi: 10.1039/c4dt02983f. Dalton Trans. 2015. PMID: 25351329

2

The Copper bis(thiosemicarbazone) Complex Cu^II(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu.

Huuskonen MT, Tuo QZ, Loppi S, Dhungana H, Korhonen P, McInnes LE, Donnelly PS, Grubman A, Wojciechowski S, Lejavova K, Pomeshchik Y, Periviita L, Kosonen L, Giordano M, Walker FR, Liu R, Bush AI, Koistinaho J, Malm T, White AR, Lei P, Kanninen KM. Huuskonen MT, et al. Among authors: mcinnes le. Neurotherapeutics. 2017 Apr;14(2):519-532. doi: 10.1007/s13311-016-0504-9. Neurotherapeutics. 2017. PMID: 28050710 Free PMC article.

3

Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P-Glycoprotein Mediated Efflux.

Acevedo KM, Hayne DJ, McInnes LE, Noor A, Duncan C, Moujalled D, Volitakis I, Rigopoulos A, Barnham KJ, Villemagne VL, White AR, Donnelly PS. Acevedo KM, et al. Among authors: mcinnes le. J Med Chem. 2018 Feb 8;61(3):711-723. doi: 10.1021/acs.jmedchem.7b01158. Epub 2018 Jan 8. J Med Chem. 2018. PMID: 29232129

4

Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.

McKenzie-Nickson S, Chan J, Perez K, Hung LW, Cheng L, Sedjahtera A, Gunawan L, Adlard PA, Hayne DJ, McInnes LE, Donnelly PS, Finkelstein DI, Hill AF, Barnham KJ. McKenzie-Nickson S, et al. Among authors: mcinnes le. ACS Chem Neurosci. 2018 Nov 21;9(11):2731-2740. doi: 10.1021/acschemneuro.8b00161. Epub 2018 Jul 3. ACS Chem Neurosci. 2018. PMID: 29920069

5

Cu^II(atsm) Attenuates Neuroinflammation.

Choo XY, Liddell JR, Huuskonen MT, Grubman A, Moujalled D, Roberts J, Kysenius K, Patten L, Quek H, Oikari LE, Duncan C, James SA, McInnes LE, Hayne DJ, Donnelly PS, Pollari E, Vähätalo S, Lejavová K, Kettunen MI, Malm T, Koistinaho J, White AR, Kanninen KM. Choo XY, et al. Among authors: mcinnes le. Front Neurosci. 2018 Sep 24;12:668. doi: 10.3389/fnins.2018.00668. eCollection 2018. Front Neurosci. 2018. PMID: 30319344 Free PMC article.

6

Potential Diagnostic Imaging of Alzheimer's Disease with Copper-64 Complexes That Bind to Amyloid-β Plaques.

McInnes LE, Noor A, Kysenius K, Cullinane C, Roselt P, McLean CA, Chiu FCK, Powell AK, Crouch PJ, White JM, Donnelly PS. McInnes LE, et al. Inorg Chem. 2019 Mar 4;58(5):3382-3395. doi: 10.1021/acs.inorgchem.8b03466. Epub 2019 Feb 20. Inorg Chem. 2019. PMID: 30785268

7

A Bivalent Inhibitor of Prostate Specific Membrane Antigen Radiolabeled with Copper-64 with High Tumor Uptake and Retention.

Zia NA, Cullinane C, Van Zuylekom JK, Waldeck K, McInnes LE, Buncic G, Haskali MB, Roselt PD, Hicks RJ, Donnelly PS. Zia NA, et al. Among authors: mcinnes le. Angew Chem Int Ed Engl. 2019 Oct 14;58(42):14991-14994. doi: 10.1002/anie.201908964. Epub 2019 Sep 5. Angew Chem Int Ed Engl. 2019. PMID: 31437347

8

Identification of the Side Products That Diminish the Yields of the Monoamidated Product in Metal-Catalyzed C-H Amidation of 2-Phenylpyridine with Arylisocyanates.

McKay AI, Altalhi WAO, McInnes LE, Czyz ML, Canty AJ, Donnelly PS, O'Hair RAJ. McKay AI, et al. Among authors: mcinnes le. J Org Chem. 2020 Feb 21;85(4):2680-2687. doi: 10.1021/acs.joc.9b02831. Epub 2020 Jan 23. J Org Chem. 2020. PMID: 31971390

9

Therapeutic Efficacy of a Bivalent Inhibitor of Prostate-Specific Membrane Antigen Labeled with ⁶⁷Cu.

McInnes LE, Cullinane C, Roselt PD, Jackson S, Blyth BJ, van Dam EM, Zia NA, Harris MJ, Hicks RJ, Donnelly PS. McInnes LE, et al. J Nucl Med. 2021 Jun 1;62(6):829-832. doi: 10.2967/jnumed.120.251579. Epub 2020 Oct 16. J Nucl Med. 2021. PMID: 33067341 Free PMC article.

10

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1^G93A mice with a C57BL/6 background.

Lum JS, Brown ML, Farrawell NE, McAlary L, Ly D, Chisholm CG, Snow J, Vine KL, Karl T, Kreilaus F, McInnes LE, Nikseresht S, Donnelly PS, Crouch PJ, Yerbury JJ. Lum JS, et al. Among authors: mcinnes le. Sci Rep. 2021 Sep 29;11(1):19392. doi: 10.1038/s41598-021-98317-w. Sci Rep. 2021. PMID: 34588483 Free PMC article.

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