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Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis.
Vázquez-Borrego MC, Del Río-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, Wnek M, Cordoba-Chacon J, Waxman DJ, Puchowicz MA, McGuinness OP, Kineman RD. Vázquez-Borrego MC, et al. Among authors: mcguinness op. Metabolism. 2023 Jul;144:155589. doi: 10.1016/j.metabol.2023.155589. Epub 2023 May 13. Metabolism. 2023. PMID: 37182789 Free PMC article.
Suppression of aging in mice by the hormone Klotho.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M. Kurosu H, et al. Among authors: mcguinness op. Science. 2005 Sep 16;309(5742):1829-33. doi: 10.1126/science.1112766. Epub 2005 Aug 25. Science. 2005. PMID: 16123266 Free PMC article.
Hyperinsulinemic-euglycemic clamps in conscious, unrestrained mice.
Ayala JE, Bracy DP, Malabanan C, James FD, Ansari T, Fueger PT, McGuinness OP, Wasserman DH. Ayala JE, et al. Among authors: mcguinness op. J Vis Exp. 2011 Nov 16;(57):3188. doi: 10.3791/3188. J Vis Exp. 2011. PMID: 22126863 Free PMC article.
Incorporation of therapeutically modified bacteria into gut microbiota inhibits obesity.
Chen Z, Guo L, Zhang Y, Walzem RL, Pendergast JS, Printz RL, Morris LC, Matafonova E, Stien X, Kang L, Coulon D, McGuinness OP, Niswender KD, Davies SS. Chen Z, et al. Among authors: mcguinness op. J Clin Invest. 2014 Aug;124(8):3391-406. doi: 10.1172/JCI72517. Epub 2014 Jun 24. J Clin Invest. 2014. PMID: 24960158 Free PMC article.
Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation.
Haldar SM, Jeyaraj D, Anand P, Zhu H, Lu Y, Prosdocimo DA, Eapen B, Kawanami D, Okutsu M, Brotto L, Fujioka H, Kerner J, Rosca MG, McGuinness OP, Snow RJ, Russell AP, Gerber AN, Bai X, Yan Z, Nosek TM, Brotto M, Hoppel CL, Jain MK. Haldar SM, et al. Among authors: mcguinness op. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6739-44. doi: 10.1073/pnas.1121060109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493257 Free PMC article.
135 results