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Epinephrine inhibits PI3Kα via the Hippo kinases.
Lin TY, Ramsamooj S, Perrier T, Liberatore K, Lantier L, Vasan N, Karukurichi K, Hwang SK, Kesicki EA, Kastenhuber ER, Wiederhold T, Yaron TM, Huntsman EM, Zhu M, Ma Y, Paddock MN, Zhang G, Hopkins BD, McGuinness O, Schwartz RE, Ersoy BA, Cantley LC, Johnson JL, Goncalves MD. Lin TY, et al. Among authors: mcguinness o. Cell Rep. 2023 Dec 26;42(12):113535. doi: 10.1016/j.celrep.2023.113535. Epub 2023 Dec 4. Cell Rep. 2023. PMID: 38060450 Free PMC article.
Mesoscale Metabolic Channeling Revealed by Multimodal Microscopy.
E Drigo RA, Habashy A, Acree C, Kim KY, Deerinck T, Patterson E, Lantier L, McGuinness O, Ellisman M. E Drigo RA, et al. Among authors: mcguinness o. Res Sq [Preprint]. 2024 Apr 17:rs.3.rs-4096781. doi: 10.21203/rs.3.rs-4096781/v1. Res Sq. 2024. PMID: 38699373 Free PMC article. Preprint.
Insulin at the intersection of thermoregulation and glucose homeostasis.
Winn NC, Schleh MW, Garcia JN, Lantier L, McGuinness OP, Blair JA, Hasty AH, Wasserman DH. Winn NC, et al. Among authors: mcguinness op. Mol Metab. 2024 Mar;81:101901. doi: 10.1016/j.molmet.2024.101901. Epub 2024 Feb 13. Mol Metab. 2024. PMID: 38354854 Free PMC article.
Insulin at the Intersection of Thermoregulation and Glucose Homeostasis.
Winn NC, Schleh MW, Garcia JN, Lantier L, McGuinness OP, Blair JA, Hasty AH, Wasserman DH. Winn NC, et al. Among authors: mcguinness op. bioRxiv [Preprint]. 2023 Nov 17:2023.11.17.566254. doi: 10.1101/2023.11.17.566254. bioRxiv. 2023. PMID: 38014310 Free PMC article. Updated. Preprint.
Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity.
Ceddia RP, Zurawski Z, Thompson Gray A, Adegboye F, McDonald-Boyer A, Shi F, Liu D, Maldonado J, Feng J, Li Y, Alford S, Ayala JE, McGuinness OP, Collins S, Hamm HE. Ceddia RP, et al. Among authors: mcguinness op. J Clin Invest. 2023 Oct 2;133(19):e160617. doi: 10.1172/JCI160617. J Clin Invest. 2023. PMID: 37561580 Free PMC article.
Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis.
Vázquez-Borrego MC, Del Río-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, Wnek M, Cordoba-Chacon J, Waxman DJ, Puchowicz MA, McGuinness OP, Kineman RD. Vázquez-Borrego MC, et al. Among authors: mcguinness op. Metabolism. 2023 Jul;144:155589. doi: 10.1016/j.metabol.2023.155589. Epub 2023 May 13. Metabolism. 2023. PMID: 37182789 Free PMC article.
Peeling back the layers of the glucose clamp.
Ayala JE, Lantier L, McGuinness OP, Wasserman DH. Ayala JE, et al. Among authors: mcguinness op. Nat Metab. 2022 May;4(5):496-498. doi: 10.1038/s42255-022-00573-1. Nat Metab. 2022. PMID: 35477775 No abstract available.
150 results