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Page 1
Characterization and engineering of a two-enzyme system for plastics depolymerization.
Knott BC, Erickson E, Allen MD, Gado JE, Graham R, Kearns FL, Pardo I, Topuzlu E, Anderson JJ, Austin HP, Dominick G, Johnson CW, Rorrer NA, Szostkiewicz CJ, Copié V, Payne CM, Woodcock HL, Donohoe BS, Beckham GT, McGeehan JE. Knott BC, et al. Among authors: mcgeehan je. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25476-25485. doi: 10.1073/pnas.2006753117. Epub 2020 Sep 28. Proc Natl Acad Sci U S A. 2020. PMID: 32989159 Free PMC article.
Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance.
Kern M, McGeehan JE, Streeter SD, Martin RN, Besser K, Elias L, Eborall W, Malyon GP, Payne CM, Himmel ME, Schnorr K, Beckham GT, Cragg SM, Bruce NC, McQueen-Mason SJ. Kern M, et al. Among authors: mcgeehan je. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10189-94. doi: 10.1073/pnas.1301502110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733951 Free PMC article.
Lignocellulose degradation mechanisms across the Tree of Life.
Cragg SM, Beckham GT, Bruce NC, Bugg TD, Distel DL, Dupree P, Etxabe AG, Goodell BS, Jellison J, McGeehan JE, McQueen-Mason SJ, Schnorr K, Walton PH, Watts JE, Zimmer M. Cragg SM, et al. Among authors: mcgeehan je. Curr Opin Chem Biol. 2015 Dec;29:108-19. doi: 10.1016/j.cbpa.2015.10.018. Epub 2015 Nov 14. Curr Opin Chem Biol. 2015. PMID: 26583519 Free PMC article. Review.
Characterization and engineering of a plastic-degrading aromatic polyesterase.
Austin HP, Allen MD, Donohoe BS, Rorrer NA, Kearns FL, Silveira RL, Pollard BC, Dominick G, Duman R, El Omari K, Mykhaylyk V, Wagner A, Michener WE, Amore A, Skaf MS, Crowley MF, Thorne AW, Johnson CW, Woodcock HL, McGeehan JE, Beckham GT. Austin HP, et al. Among authors: mcgeehan je. Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4350-E4357. doi: 10.1073/pnas.1718804115. Epub 2018 Apr 17. Proc Natl Acad Sci U S A. 2018. PMID: 29666242 Free PMC article.
A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion.
Mallinson SJB, Machovina MM, Silveira RL, Garcia-Borràs M, Gallup N, Johnson CW, Allen MD, Skaf MS, Crowley MF, Neidle EL, Houk KN, Beckham GT, DuBois JL, McGeehan JE. Mallinson SJB, et al. Among authors: mcgeehan je. Nat Commun. 2018 Jun 27;9(1):2487. doi: 10.1038/s41467-018-04878-2. Nat Commun. 2018. PMID: 29950589 Free PMC article.
Enabling microbial syringol conversion through structure-guided protein engineering.
Machovina MM, Mallinson SJB, Knott BC, Meyers AW, Garcia-Borràs M, Bu L, Gado JE, Oliver A, Schmidt GP, Hinchen DJ, Crowley MF, Johnson CW, Neidle EL, Payne CM, Houk KN, Beckham GT, McGeehan JE, DuBois JL. Machovina MM, et al. Among authors: mcgeehan je. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13970-13976. doi: 10.1073/pnas.1820001116. Epub 2019 Jun 24. Proc Natl Acad Sci U S A. 2019. PMID: 31235604 Free PMC article.
Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes.
Ellis ES, Hinchen DJ, Bleem A, Bu L, Mallinson SJB, Allen MD, Streit BR, Machovina MM, Doolin QV, Michener WE, Johnson CW, Knott BC, Beckham GT, McGeehan JE, DuBois JL. Ellis ES, et al. Among authors: mcgeehan je. JACS Au. 2021 Feb 4;1(3):252-261. doi: 10.1021/jacsau.0c00103. eCollection 2021 Mar 22. JACS Au. 2021. PMID: 34467290 Free PMC article.
Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation.
Erickson E, Shakespeare TJ, Bratti F, Buss BL, Graham R, Hawkins MA, König G, Michener WE, Miscall J, Ramirez KJ, Rorrer NA, Zahn M, Pickford AR, McGeehan JE, Beckham GT. Erickson E, et al. Among authors: mcgeehan je. ChemSusChem. 2022 Jan 10;15(1):e202101932. doi: 10.1002/cssc.202101932. Epub 2021 Nov 5. ChemSusChem. 2022. PMID: 34587366
Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation.
Erickson E, Shakespeare TJ, Bratti F, Buss BL, Graham R, Hawkins MA, König G, Michener WE, Miscall J, Ramirez KJ, Rorrer NA, Zahn M, Pickford AR, McGeehan JE, Beckham GT. Erickson E, et al. Among authors: mcgeehan je. ChemSusChem. 2022 Jan 10;15(1):e202102517. doi: 10.1002/cssc.202102517. Epub 2021 Dec 16. ChemSusChem. 2022. PMID: 34914860
Debottlenecking 4-hydroxybenzoate hydroxylation in Pseudomonas putida KT2440 improves muconate productivity from p-coumarate.
Kuatsjah E, Johnson CW, Salvachúa D, Werner AZ, Zahn M, Szostkiewicz CJ, Singer CA, Dominick G, Okekeogbu I, Haugen SJ, Woodworth SP, Ramirez KJ, Giannone RJ, Hettich RL, McGeehan JE, Beckham GT. Kuatsjah E, et al. Among authors: mcgeehan je. Metab Eng. 2022 Mar;70:31-42. doi: 10.1016/j.ymben.2021.12.010. Epub 2022 Jan 1. Metab Eng. 2022. PMID: 34982998
66 results