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DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification.
Camacho CV, Todorova PK, Hardebeck MC, Tomimatsu N, Gil del Alcazar CR, Ilcheva M, Mukherjee B, McEllin B, Vemireddy V, Hatanpaa K, Story MD, Habib AA, Murty VV, Bachoo R, Burma S. Camacho CV, et al. Among authors: mcellin b. Oncogene. 2015 Feb 19;34(8):1064-72. doi: 10.1038/onc.2014.29. Epub 2014 Mar 17. Oncogene. 2015. PMID: 24632607 Free PMC article.
Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.
Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA, Xie XJ, Nirodi CS, Saha D, Story MD, Balajee AS, Bachoo RM, Boothman DA, Burma S. Camacho CV, et al. Among authors: mcellin b. Carcinogenesis. 2010 Oct;31(10):1889-96. doi: 10.1093/carcin/bgq153. Epub 2010 Jul 26. Carcinogenesis. 2010. PMID: 20663777 Free PMC article.
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, Hatanpaa KJ, Mickey B, Madden C, Maher E, Boothman DA, Furnari F, Cavenee WK, Bachoo RM, Burma S. Mukherjee B, et al. Among authors: mcellin b. Cancer Res. 2009 May 15;69(10):4252-9. doi: 10.1158/0008-5472.CAN-08-4853. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435898 Free PMC article.