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Clinical remission in severe asthma with biologic therapy: an analysis from the UK Severe Asthma Registry.
McDowell PJ, McDowell R, Busby J, Eastwood MC, Patel PH, Jackson DJ, Mansur A, Patel M, Burhan H, Doe S, Chaudhuri R, Gore R, Dodd JW, Subramanian D, Brown T, Heaney LG; UK Severe Asthma Registry. McDowell PJ, et al. Eur Respir J. 2023 Dec 14;62(6):2300819. doi: 10.1183/13993003.00819-2023. Print 2023 Dec. Eur Respir J. 2023. PMID: 37857423 Free PMC article.
The inflammatory profile of exacerbations in patients with severe refractory eosinophilic asthma receiving mepolizumab (the MEX study): a prospective observational study.
McDowell PJ, Diver S, Yang F, Borg C, Busby J, Brown V, Shrimanker R, Cox C, Brightling CE, Chaudhuri R, Pavord ID, Heaney LG; Medical Research Council: Refractory Asthma Stratification Programme (RASP-UK Consortium). McDowell PJ, et al. Lancet Respir Med. 2021 Oct;9(10):1174-1184. doi: 10.1016/S2213-2600(21)00004-7. Epub 2021 May 7. Lancet Respir Med. 2021. PMID: 33971168
Exacerbation Profile and Risk Factors in a Type-2-Low Enriched Severe Asthma Cohort: A Clinical Trial to Assess Asthma Exacerbation Phenotypes.
McDowell PJ, Busby J, Hanratty CE, Djukanovic R, Woodcock A, Walker S, Hardman TC, Arron JR, Choy DF, Bradding P, Brightling CE, Chaudhuri R, Cowan D, Mansur AH, Fowler SJ, Diver SE, Howarth P, Lordan J, Menzies-Gow A, Harrison T, Robinson DS, Holweg CTJ, Matthews JG, Pavord ID, Heaney LG. McDowell PJ, et al. Am J Respir Crit Care Med. 2022 Sep 1;206(5):545-553. doi: 10.1164/rccm.202201-0129OC. Am J Respir Crit Care Med. 2022. PMID: 35549845 Free PMC article. Clinical Trial.
Relationship between inflammatory status and microbial composition in severe asthma and during exacerbation.
Diver S, Haldar K, McDowell PJ, Busby J, Mistry V, Micieli C, Brown V, Cox C, Yang F, Borg C, Shrimanker R, Ramsheh MY, Hardman T, Arron J, Bradding P, Cowan D, Mansur AH, Fowler SJ, Lordan J, Menzies-Gow A, Robinson D, Matthews J, Pavord ID, Chaudhuri R, Heaney LG, Barer MR, Brightling C; Medical Research Council: Refractory Asthma Stratification Programme (RASP-UK Consortium). Diver S, et al. Among authors: mcdowell pj. Allergy. 2022 Nov;77(11):3362-3376. doi: 10.1111/all.15425. Epub 2022 Jul 15. Allergy. 2022. PMID: 35778780 Free article.
Corrigendum to The Glucocorticoid Toxicity Index: Measuring Change in Glucocorticoid Toxicity Over Time [Seminars in Arthritis and Rheumatism Volume 55, 152010].
Stone JH, McDowell PJ, Jayne DRW, Merkel PA, Robson J, Patel NJ, Zhang Y, Yue H, Bekker P, Heaney LG. Stone JH, et al. Among authors: mcdowell pj. Semin Arthritis Rheum. 2023 Feb;58:152124. doi: 10.1016/j.semarthrit.2022.152124. Epub 2022 Dec 5. Semin Arthritis Rheum. 2023. PMID: 36473338 Free article. No abstract available.
Blood transcriptomic signature in type-2 biomarker-low severe asthma and asthma control.
Zeng X, Qing J, Li CM, Lu J, Yamawaki T, Hsu YH, Vander Lugt B, Hsu H, Busby J, McDowell PJ, Jackson DJ, Djukanovic R, Matthews JG, Arron JR, Bradding P, Brightling CE, Chaudhuri R, Choy DF, Cowan D, Fowler SJ, Hardman TC, Harrison T, Howarth P, Lordan J, Mansur AH, Menzies-Gow A, Pavord ID, Walker S, Woodcock A, Heaney LG; investigators for the UK MRC Refractory Asthma Stratification Program (RASP-UK). Zeng X, et al. Among authors: mcdowell pj. J Allergy Clin Immunol. 2023 Oct;152(4):876-886. doi: 10.1016/j.jaci.2023.05.023. Epub 2023 Jun 12. J Allergy Clin Immunol. 2023. PMID: 37315813 Free article. Clinical Trial.
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