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Page 1
High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.
Setliff I, Shiakolas AR, Pilewski KA, Murji AA, Mapengo RE, Janowska K, Richardson S, Oosthuysen C, Raju N, Ronsard L, Kanekiyo M, Qin JS, Kramer KJ, Greenplate AR, McDonnell WJ, Graham BS, Connors M, Lingwood D, Acharya P, Morris L, Georgiev IS. Setliff I, et al. Among authors: mcdonnell wj. Cell. 2019 Dec 12;179(7):1636-1646.e15. doi: 10.1016/j.cell.2019.11.003. Epub 2019 Nov 28. Cell. 2019. PMID: 31787378 Free PMC article.
Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.
Setliff I, McDonnell WJ, Raju N, Bombardi RG, Murji AA, Scheepers C, Ziki R, Mynhardt C, Shepherd BE, Mamchak AA, Garrett N, Karim SA, Mallal SA, Crowe JE Jr, Morris L, Georgiev IS. Setliff I, et al. Among authors: mcdonnell wj. Cell Host Microbe. 2018 Jun 13;23(6):845-854.e6. doi: 10.1016/j.chom.2018.05.001. Epub 2018 May 31. Cell Host Microbe. 2018. PMID: 29861170 Free PMC article.
Adipose Tissue is Enriched for Activated and Late-Differentiated CD8+ T Cells and Shows Distinct CD8+ Receptor Usage, Compared With Blood in HIV-Infected Persons.
Koethe JR, McDonnell W, Kennedy A, Abana CO, Pilkinton M, Setliff I, Georgiev I, Barnett L, Hager CC, Smith R, Kalams SA, Hasty A, Mallal S. Koethe JR, et al. J Acquir Immune Defic Syndr. 2018 Feb 1;77(2):e14-e21. doi: 10.1097/QAI.0000000000001573. J Acquir Immune Defic Syndr. 2018. PMID: 29040163 Free PMC article.
Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells.
Wanjalla CN, McDonnell WJ, Ram R, Chopra A, Gangula R, Leary S, Mashayekhi M, Simmons JD, Warren CM, Bailin S, Gabriel CL, Guo L, Furch BD, Lima MC, Woodward BO, Hannah L, Pilkinton MA, Fuller DT, Kawai K, Virmani R, Finn AV, Hasty AH, Mallal SA, Kalams SA, Koethe JR. Wanjalla CN, et al. Among authors: mcdonnell wj. Cell Rep Med. 2021 Feb 16;2(2):100205. doi: 10.1016/j.xcrm.2021.100205. eCollection 2021 Feb 16. Cell Rep Med. 2021. PMID: 33665640 Free PMC article.
Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV.
Currenti J, Chopra A, John M, Leary S, McKinnon E, Alves E, Pilkinton M, Smith R, Barnett L, McDonnell WJ, Lucas M, Noel F, Mallal S, Conrad JA, Kalams SA, Gaudieri S. Currenti J, et al. Among authors: mcdonnell wj. PLoS Pathog. 2019 Dec 10;15(12):e1008177. doi: 10.1371/journal.ppat.1008177. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31821379 Free PMC article.
In chronic infection, HIV gag-specific CD4+ T cell receptor diversity is higher than CD8+ T cell receptor diversity and is associated with less HIV quasispecies diversity.
Pilkinton MA, McDonnell WJ, Barnett L, Chopra A, Gangula R, White KD, Leary S, Currenti J, Gaudieri S, Mallal SA, Kalams SA. Pilkinton MA, et al. Among authors: mcdonnell wj. J Virol. 2021 Mar 25;95(8):e02380-20. doi: 10.1128/JVI.02380-20. Epub 2021 Feb 3. J Virol. 2021. PMID: 33536169 Free PMC article.
Cross-Reactivity to Mutated Viral Immune Targets Can Influence CD8+ T Cell Functionality: An Alternative Viral Adaptation Strategy.
Currenti J, Law BMP, Qin K, John M, Pilkinton MA, Bansal A, Leary S, Ram R, Chopra A, Gangula R, Yue L, Warren C, Barnett L, Alves E, McDonnell WJ, Sooda A, Heath SL, Mallal S, Goepfert P, Kalams SA, Gaudieri S. Currenti J, et al. Among authors: mcdonnell wj. Front Immunol. 2021 Oct 26;12:746986. doi: 10.3389/fimmu.2021.746986. eCollection 2021. Front Immunol. 2021. PMID: 34764960 Free PMC article.
IgG4-related disease: Association with a rare gene variant expressed in cytotoxic T cells.
Newman JH, Shaver A, Sheehan JH, Mallal S, Stone JH, Pillai S, Bastarache L, Riebau D, Allard-Chamard H, Stone WM, Perugino C, Pilkinton M, Smith SA, McDonnell WJ, Capra JA, Meiler J, Cogan J, Xing K, Mahajan VS, Mattoo H, Hamid R, Phillips JA 3rd; Undiagnosed Disease Network. Newman JH, et al. Among authors: mcdonnell wj. Mol Genet Genomic Med. 2019 Jun;7(6):e686. doi: 10.1002/mgg3.686. Epub 2019 Apr 16. Mol Genet Genomic Med. 2019. PMID: 30993913 Free PMC article.
Adipose Tissue T Cells in HIV/SIV Infection.
Wanjalla CN, McDonnell WJ, Koethe JR. Wanjalla CN, et al. Among authors: mcdonnell wj. Front Immunol. 2018 Dec 3;9:2730. doi: 10.3389/fimmu.2018.02730. eCollection 2018. Front Immunol. 2018. PMID: 30559739 Free PMC article. Review.
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