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Locating the stem cell niche and tracing hepatocyte lineages in human liver.
Fellous TG, Islam S, Tadrous PJ, Elia G, Kocher HM, Bhattacharya S, Mears L, Turnbull DM, Taylor RW, Greaves LC, Chinnery PF, Taylor G, McDonald SA, Wright NA, Alison MR. Fellous TG, et al. Among authors: mcdonald sa. Hepatology. 2009 May;49(5):1655-63. doi: 10.1002/hep.22791. Hepatology. 2009. PMID: 19309719
Intestinal stem cells.
Leedham SJ, Brittan M, McDonald SA, Wright NA. Leedham SJ, et al. Among authors: mcdonald sa. J Cell Mol Med. 2005 Jan-Mar;9(1):11-24. doi: 10.1111/j.1582-4934.2005.tb00333.x. J Cell Mol Med. 2005. PMID: 15784161 Free PMC article. Review.
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.
Greaves LC, Preston SL, Tadrous PJ, Taylor RW, Barron MJ, Oukrif D, Leedham SJ, Deheragoda M, Sasieni P, Novelli MR, Jankowski JA, Turnbull DM, Wright NA, McDonald SA. Greaves LC, et al. Among authors: mcdonald sa. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):714-9. doi: 10.1073/pnas.0505903103. Epub 2006 Jan 6. Proc Natl Acad Sci U S A. 2006. PMID: 16407113 Free PMC article.
Mechanisms of disease: from stem cells to colorectal cancer.
McDonald SA, Preston SL, Lovell MJ, Wright NA, Jankowski JA. McDonald SA, et al. Nat Clin Pract Gastroenterol Hepatol. 2006 May;3(5):267-74. doi: 10.1038/ncpgasthep0473. Nat Clin Pract Gastroenterol Hepatol. 2006. PMID: 16673006 Review.
Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells.
McDonald SA, Greaves LC, Gutierrez-Gonzalez L, Rodriguez-Justo M, Deheragoda M, Leedham SJ, Taylor RW, Lee CY, Preston SL, Lovell M, Hunt T, Elia G, Oukrif D, Harrison R, Novelli MR, Mitchell I, Stoker DL, Turnbull DM, Jankowski JA, Wright NA. McDonald SA, et al. Gastroenterology. 2008 Feb;134(2):500-10. doi: 10.1053/j.gastro.2007.11.035. Epub 2007 Nov 28. Gastroenterology. 2008. PMID: 18242216
Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.
Milicic A, Harrison LA, Goodlad RA, Hardy RG, Nicholson AM, Presz M, Sieber O, Santander S, Pringle JH, Mandir N, East P, Obszynska J, Sanders S, Piazuelo E, Shaw J, Harrison R, Tomlinson IP, McDonald SA, Wright NA, Jankowski JA. Milicic A, et al. Among authors: mcdonald sa. Cancer Res. 2008 Oct 1;68(19):7760-8. doi: 10.1158/0008-5472.CAN-08-0020. Cancer Res. 2008. PMID: 18829530 Free PMC article.
Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations.
Gutierrez-Gonzalez L, Deheragoda M, Elia G, Leedham SJ, Shankar A, Imber C, Jankowski JA, Turnbull DM, Novelli M, Wright NA, McDonald SA. Gutierrez-Gonzalez L, et al. Among authors: mcdonald sa. J Pathol. 2009 Mar;217(4):489-96. doi: 10.1002/path.2502. J Pathol. 2009. PMID: 19156773
316 results