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Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice.
Fessler MB, Madenspacher JH, Baker PJ, Hilligan KL, Bohrer AC, Castro E, Meacham J, Chen SH, Johnson RF, McDonald JG, Martin NP, Tucker CJ, Mahapatra D, Cesta M, Mayer-Barber KD. Fessler MB, et al. Among authors: mcdonald jg. Am J Respir Cell Mol Biol. 2023 Dec;69(6):638-648. doi: 10.1165/rcmb.2023-0007OC. Am J Respir Cell Mol Biol. 2023. PMID: 37578898 Free PMC article.
Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation.
Madenspacher JH, Morrell ED, Gowdy KM, McDonald JG, Thompson BM, Muse G, Martinez J, Thomas S, Mikacenic C, Nick JA, Abraham E, Garantziotis S, Stapleton RD, Meacham JM, Thomassen MJ, Janssen WJ, Cook DN, Wurfel MM, Fessler MB. Madenspacher JH, et al. Among authors: mcdonald jg. JCI Insight. 2020 Jun 4;5(11):e137189. doi: 10.1172/jci.insight.137189. JCI Insight. 2020. PMID: 32343675 Free PMC article.
25-Hydroxycholesterol exacerbates vascular leak during acute lung injury.
Madenspacher JH, Morrell ED, McDonald JG, Thompson BM, Li Y, Birukov KG, Birukova AA, Stapleton RD, Alejo A, Karmaus PW, Meacham JM, Rai P, Mikacenic C, Wurfel MM, Fessler MB. Madenspacher JH, et al. Among authors: mcdonald jg. JCI Insight. 2023 Apr 10;8(7):e155448. doi: 10.1172/jci.insight.155448. JCI Insight. 2023. PMID: 36821369 Free PMC article.
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
Wu Q, Ishikawa T, Sirianni R, Tang H, McDonald JG, Yuhanna IS, Thompson B, Girard L, Mineo C, Brekken RA, Umetani M, Euhus DM, Xie Y, Shaul PW. Wu Q, et al. Among authors: mcdonald jg. Cell Rep. 2013 Nov 14;5(3):637-45. doi: 10.1016/j.celrep.2013.10.006. Epub 2013 Nov 7. Cell Rep. 2013. PMID: 24210818 Free PMC article.
134 results