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Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease.
Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, Canela EI, Ginés S, McCormick PJ. Moreno-Delgado D, et al. Among authors: mccormick pj. Elife. 2020 Jun 9;9:e51093. doi: 10.7554/eLife.51093. Elife. 2020. PMID: 32513388 Free PMC article.
Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs.
Navarro G, Cordomí A, Zelman-Femiak M, Brugarolas M, Moreno E, Aguinaga D, Perez-Benito L, Cortés A, Casadó V, Mallol J, Canela EI, Lluís C, Pardo L, García-Sáez AJ, McCormick PJ, Franco R. Navarro G, et al. Among authors: mccormick pj. BMC Biol. 2016 Apr 5;14:26. doi: 10.1186/s12915-016-0247-4. BMC Biol. 2016. PMID: 27048449 Free PMC article.
Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.
Guitart X, Navarro G, Moreno E, Yano H, Cai NS, Sánchez-Soto M, Kumar-Barodia S, Naidu YT, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, McCormick PJ, Ferré S. Guitart X, et al. Among authors: mccormick pj. Mol Pharmacol. 2014 Oct;86(4):417-29. doi: 10.1124/mol.114.093096. Epub 2014 Aug 5. Mol Pharmacol. 2014. PMID: 25097189 Free PMC article.
Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure.
Busnelli M, Kleinau G, Muttenthaler M, Stoev S, Manning M, Bibic L, Howell LA, McCormick PJ, Di Lascio S, Braida D, Sala M, Rovati GE, Bellini T, Chini B. Busnelli M, et al. Among authors: mccormick pj. J Med Chem. 2016 Aug 11;59(15):7152-66. doi: 10.1021/acs.jmedchem.6b00564. Epub 2016 Jul 28. J Med Chem. 2016. PMID: 27420737 Free article.
175 results