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Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Chen S, Vedula RS, Cuevas-Navarro A, Lu B, Hogg SJ, Wang E, Benbarche S, Knorr K, Kim WJ, Stanley RF, Cho H, Erickson C, Singer M, Cui D, Tittley S, Durham BH, Pavletich TS, Fiala E, Walsh MF, Inoue D, Monette S, Taylor J, Rosen N, McCormick F, Lindsley RC, Castel P, Abdel-Wahab O. Chen S, et al. Among authors: mccormick f. Cancer Discov. 2022 Oct 5;12(10):2434-2453. doi: 10.1158/2159-8290.CD-21-1631. Cancer Discov. 2022. PMID: 35904492 Free PMC article.
A conditional feedback loop regulates Ras activity through EphA2.
Macrae M, Neve RM, Rodriguez-Viciana P, Haqq C, Yeh J, Chen C, Gray JW, McCormick F. Macrae M, et al. Among authors: mccormick f. Cancer Cell. 2005 Aug;8(2):111-8. doi: 10.1016/j.ccr.2005.07.005. Cancer Cell. 2005. PMID: 16098464 Free article.
Ras signaling and therapies.
Young A, Lyons J, Miller AL, Phan VT, Alarcón IR, McCormick F. Young A, et al. Among authors: mccormick f. Adv Cancer Res. 2009;102:1-17. doi: 10.1016/S0065-230X(09)02001-6. Adv Cancer Res. 2009. PMID: 19595305 Review.
Therapeutic strategies for targeting ras proteins.
Gysin S, Salt M, Young A, McCormick F. Gysin S, et al. Among authors: mccormick f. Genes Cancer. 2011 Mar;2(3):359-72. doi: 10.1177/1947601911412376. Genes Cancer. 2011. PMID: 21779505 Free PMC article.
Killing tumors by keeping ras and PI3' kinase apart.
Yuan TL, McCormick F. Yuan TL, et al. Among authors: mccormick f. Cancer Cell. 2013 Nov 11;24(5):562-3. doi: 10.1016/j.ccr.2013.10.015. Cancer Cell. 2013. PMID: 24229705 Free article.
Dragging ras back in the ring.
Stephen AG, Esposito D, Bagni RK, McCormick F. Stephen AG, et al. Among authors: mccormick f. Cancer Cell. 2014 Mar 17;25(3):272-81. doi: 10.1016/j.ccr.2014.02.017. Cancer Cell. 2014. PMID: 24651010 Free article. Review.
Development of siRNA payloads to target KRAS-mutant cancer.
Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW. Yuan TL, et al. Among authors: mccormick f. Cancer Discov. 2014 Oct;4(10):1182-1197. doi: 10.1158/2159-8290.CD-13-0900. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100204 Free PMC article.
591 results