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A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.
Zhao X, Zeng W, Xu H, Sun Z, Hu Y, Peng B, McBride JD, Duan J, Deng J, Zhang B, Kim SJ, Zoll B, Saito T, Sasaguri H, Saido TC, Ballatore C, Yao H, Wang Z, Trojanowski JQ, Brunden KR, Lee VM, He Z. Zhao X, et al. Among authors: mcbride jd. Sci Transl Med. 2023 Sep 13;15(713):eabo6889. doi: 10.1126/scitranslmed.abo6889. Epub 2023 Sep 13. Sci Transl Med. 2023. PMID: 37703352 Free PMC article.
Transmission of tauopathy strains is independent of their isoform composition.
He Z, McBride JD, Xu H, Changolkar L, Kim SJ, Zhang B, Narasimhan S, Gibbons GS, Guo JL, Kozak M, Schellenberg GD, Trojanowski JQ, Lee VM. He Z, et al. Among authors: mcbride jd. Nat Commun. 2020 Jan 7;11(1):7. doi: 10.1038/s41467-019-13787-x. Nat Commun. 2020. PMID: 31911587 Free PMC article.
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.
Xu H, O'Reilly M, Gibbons GS, Changolkar L, McBride JD, Riddle DM, Zhang B, Stieber A, Nirschl J, Kim SJ, Hoxha KH, Brunden KR, Schellenberg GD, Trojanowski JQ, Lee VM. Xu H, et al. Among authors: mcbride jd. Acta Neuropathol. 2021 Feb;141(2):193-215. doi: 10.1007/s00401-020-02253-4. Epub 2021 Jan 1. Acta Neuropathol. 2021. PMID: 33385254 Free PMC article.
55 results