Mazzucato P - Search Results

1

A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells.

Hazelbaker DZ, Beccard A, Angelini G, Mazzucato P, Messana A, Lam D, Eggan K, Barrett LE. Hazelbaker DZ, et al. Among authors: mazzucato p. Sci Rep. 2020 Jan 20;10(1):635. doi: 10.1038/s41598-020-57500-1. Sci Rep. 2020. PMID: 31959800 Free PMC article.

2

A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease.

Hazelbaker DZ, Beccard A, Bara AM, Dabkowski N, Messana A, Mazzucato P, Lam D, Manning D, Eggan K, Barrett LE. Hazelbaker DZ, et al. Among authors: mazzucato p. Stem Cell Reports. 2017 Oct 10;9(4):1315-1327. doi: 10.1016/j.stemcr.2017.09.006. Stem Cell Reports. 2017. PMID: 29020615 Free PMC article.

3

De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells.

Fukuda A, Hazelbaker DZ, Motosugi N, Hao J, Limone F, Beccard A, Mazzucato P, Messana A, Okada C, San Juan IG, Qian M, Umezawa A, Akutsu H, Barrett LE, Eggan K. Fukuda A, et al. Among authors: mazzucato p. Stem Cell Reports. 2021 Sep 14;16(9):2138-2148. doi: 10.1016/j.stemcr.2021.07.015. Epub 2021 Aug 19. Stem Cell Reports. 2021. PMID: 34416176 Free PMC article.

4

Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models.

Susco SG, Ghosh S, Mazzucato P, Angelini G, Beccard A, Barrera V, Berryer MH, Messana A, Lam D, Hazelbaker DZ, Barrett LE. Susco SG, et al. Among authors: mazzucato p. Cell Rep. 2022 Sep 6;40(10):111312. doi: 10.1016/j.celrep.2022.111312. Cell Rep. 2022. PMID: 36070702 Free PMC article.

5

In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities.

Chaim IA, Nagel ZD, Jordan JJ, Mazzucato P, Ngo LP, Samson LD. Chaim IA, et al. Among authors: mazzucato p. Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10379-E10388. doi: 10.1073/pnas.1712032114. Epub 2017 Nov 9. Proc Natl Acad Sci U S A. 2017. PMID: 29122935 Free PMC article.

6

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.

Nagel ZD, Margulies CM, Chaim IA, McRee SK, Mazzucato P, Ahmad A, Abo RP, Butty VL, Forget AL, Samson LD. Nagel ZD, et al. Among authors: mazzucato p. Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1823-32. doi: 10.1073/pnas.1401182111. Epub 2014 Apr 22. Proc Natl Acad Sci U S A. 2014. PMID: 24757057 Free PMC article.

7

Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide.

McFaline-Figueroa JL, Braun CJ, Stanciu M, Nagel ZD, Mazzucato P, Sangaraju D, Cerniauskas E, Barford K, Vargas A, Chen Y, Tretyakova N, Lees JA, Hemann MT, White FM, Samson LD. McFaline-Figueroa JL, et al. Among authors: mazzucato p. Cancer Res. 2015 Aug 1;75(15):3127-38. doi: 10.1158/0008-5472.CAN-14-3616. Epub 2015 May 29. Cancer Res. 2015. PMID: 26025730 Free PMC article.

8

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.

Nagel ZD, Kitange GJ, Gupta SK, Joughin BA, Chaim IA, Mazzucato P, Lauffenburger DA, Sarkaria JN, Samson LD. Nagel ZD, et al. Among authors: mazzucato p. Cancer Res. 2017 Jan 1;77(1):198-206. doi: 10.1158/0008-5472.CAN-16-1151. Epub 2016 Oct 28. Cancer Res. 2017. PMID: 27793847 Free PMC article.

9

Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells.

Nagel ZD, Beharry AA, Mazzucato P, Kitange GJ, Sarkaria JN, Kool ET, Samson LD. Nagel ZD, et al. Among authors: mazzucato p. PLoS One. 2019 Feb 27;14(2):e0208341. doi: 10.1371/journal.pone.0208341. eCollection 2019. PLoS One. 2019. PMID: 30811507 Free PMC article.

10

CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage.

Ngo LP, Kaushal S, Chaim IA, Mazzucato P, Ricciardi C, Samson LD, Nagel ZD, Engelward BP. Ngo LP, et al. Among authors: mazzucato p. Free Radic Biol Med. 2021 Oct;174:89-99. doi: 10.1016/j.freeradbiomed.2021.07.033. Epub 2021 Jul 26. Free Radic Biol Med. 2021. PMID: 34324980 Free PMC article.

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