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A highly efficient transgene knock-in technology in clinically relevant cell types.
Allen AG, Khan SQ, Margulies CM, Viswanathan R, Lele S, Blaha L, Scott SN, Izzo KM, Gerew A, Pattali R, Cochran NR, Holland CS, Zhao AH, Sherman SE, Jaskolka MC, Wu M, Wilson AC, Sun X, Ciulla DM, Zhang D, Nelson JD, Zhang P, Mazzucato P, Huang Y, Giannoukos G, Marco E, Nehil M, Follit JA, Chang KH, Shearman MS, Wilson CJ, Zuris JA. Allen AG, et al. Among authors: mazzucato p. Nat Biotechnol. 2024 Mar;42(3):458-469. doi: 10.1038/s41587-023-01779-8. Epub 2023 May 1. Nat Biotechnol. 2024. PMID: 37127662
De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells.
Fukuda A, Hazelbaker DZ, Motosugi N, Hao J, Limone F, Beccard A, Mazzucato P, Messana A, Okada C, San Juan IG, Qian M, Umezawa A, Akutsu H, Barrett LE, Eggan K. Fukuda A, et al. Among authors: mazzucato p. Stem Cell Reports. 2021 Sep 14;16(9):2138-2148. doi: 10.1016/j.stemcr.2021.07.015. Epub 2021 Aug 19. Stem Cell Reports. 2021. PMID: 34416176 Free PMC article.
CometChip enables parallel analysis of multiple DNA repair activities.
Ge J, Ngo LP, Kaushal S, Tay IJ, Thadhani E, Kay JE, Mazzucato P, Chow DN, Fessler JL, Weingeist DM, Sobol RW, Samson LD, Floyd SR, Engelward BP. Ge J, et al. Among authors: mazzucato p. DNA Repair (Amst). 2021 Oct;106:103176. doi: 10.1016/j.dnarep.2021.103176. Epub 2021 Jul 10. DNA Repair (Amst). 2021. PMID: 34365116 Free PMC article.
30 results