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Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.
Kay EJ, Paterson K, Riera-Domingo C, Sumpton D, Däbritz JHM, Tardito S, Boldrini C, Hernandez-Fernaud JR, Athineos D, Dhayade S, Stepanova E, Gjerga E, Neilson LJ, Lilla S, Hedley A, Koulouras G, McGregor G, Jamieson C, Johnson RM, Park M, Kirschner K, Miller C, Kamphorst JJ, Loayza-Puch F, Saez-Rodriguez J, Mazzone M, Blyth K, Zagnoni M, Zanivan S. Kay EJ, et al. Among authors: mazzone m. Nat Metab. 2022 Aug;4(8):1084. doi: 10.1038/s42255-022-00632-7. Nat Metab. 2022. PMID: 35927357 Free PMC article. No abstract available.
The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts.
Kuchnio A, Moens S, Bruning U, Kuchnio K, Cruys B, Thienpont B, Broux M, Ungureanu AA, Leite de Oliveira R, Bruyère F, Cuervo H, Manderveld A, Carton A, Hernandez-Fernaud JR, Zanivan S, Bartic C, Foidart JM, Noel A, Vinckier S, Lambrechts D, Dewerchin M, Mazzone M, Carmeliet P. Kuchnio A, et al. Among authors: mazzone m. Cell Rep. 2015 Aug 11;12(6):992-1005. doi: 10.1016/j.celrep.2015.07.010. Epub 2015 Jul 30. Cell Rep. 2015. PMID: 26235614 Free article.
PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Deschoemaeker S, Di Conza G, Lilla S, Martín-Pérez R, Mennerich D, Boon L, Hendrikx S, Maddocks OD, Marx C, Radhakrishnan P, Prenen H, Schneider M, Myllyharju J, Kietzmann T, Vousden KH, Zanivan S, Mazzone M. Deschoemaeker S, et al. Among authors: mazzone m. EMBO Mol Med. 2015 Oct;7(10):1350-65. doi: 10.15252/emmm.201505492. EMBO Mol Med. 2015. PMID: 26290450 Free PMC article.
Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.
Hernandez-Fernaud JR, Ruengeler E, Casazza A, Neilson LJ, Pulleine E, Santi A, Ismail S, Lilla S, Dhayade S, MacPherson IR, McNeish I, Ennis D, Ali H, Kugeratski FG, Al Khamici H, van den Biggelaar M, van den Berghe PV, Cloix C, McDonald L, Millan D, Hoyle A, Kuchnio A, Carmeliet P, Valenzuela SM, Blyth K, Yin H, Mazzone M, Norman JC, Zanivan S. Hernandez-Fernaud JR, et al. Among authors: mazzone m. Nat Commun. 2017 Feb 15;8:14206. doi: 10.1038/ncomms14206. Nat Commun. 2017. PMID: 28198360 Free PMC article.
Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.
Reid SE, Kay EJ, Neilson LJ, Henze AT, Serneels J, McGhee EJ, Dhayade S, Nixon C, Mackey JB, Santi A, Swaminathan K, Athineos D, Papalazarou V, Patella F, Román-Fernández Á, ElMaghloob Y, Hernandez-Fernaud JR, Adams RH, Ismail S, Bryant DM, Salmeron-Sanchez M, Machesky LM, Carlin LM, Blyth K, Mazzone M, Zanivan S. Reid SE, et al. Among authors: mazzone m. EMBO J. 2017 Aug 15;36(16):2373-2389. doi: 10.15252/embj.201694912. Epub 2017 Jul 10. EMBO J. 2017. PMID: 28694244 Free PMC article.
Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling.
Kugeratski FG, Atkinson SJ, Neilson LJ, Lilla S, Knight JRP, Serneels J, Juin A, Ismail S, Bryant DM, Markert EK, Machesky LM, Mazzone M, Sansom OJ, Zanivan S. Kugeratski FG, et al. Among authors: mazzone m. Sci Signal. 2019 Feb 5;12(567):eaan8247. doi: 10.1126/scisignal.aan8247. Sci Signal. 2019. PMID: 30723174 Free PMC article.
PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index.
Casazza A, Van Helleputte L, Van Renterghem B, Pokreisz P, De Geest N, De Petrini M, Janssens T, Pellens M, Diricx M, Riera-Domingo C, Wozniak A, Mazzone M, Schöffski P, Defert O, Reyns G, Kindt N. Casazza A, et al. Among authors: mazzone m. Mol Cancer Ther. 2022 Apr 1;21(4):568-581. doi: 10.1158/1535-7163.MCT-21-0518. Mol Cancer Ther. 2022. PMID: 35149549 Free PMC article.
282 results