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Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models.
Caon E, Martins M, Hodgetts H, Blanken L, Vilia MG, Levi A, Thanapirom K, Al-Akkad W, Abu-Hanna J, Baselli G, Hall AR, Luong TV, Taanman JW, Vacca M, Valenti L, Romeo S, Mazza G, Pinzani M, Rombouts K. Caon E, et al. Among authors: mazza g. J Hepatol. 2024 Feb 15:S0168-8278(24)00110-7. doi: 10.1016/j.jhep.2024.01.032. Online ahead of print. J Hepatol. 2024. PMID: 38365182 Free article.
The adenosine monophosphate-activated protein kinase-vacuolar adenosine triphosphatase-pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells.
Marrone G, De Chiara F, Böttcher K, Levi A, Dhar D, Longato L, Mazza G, Zhang Z, Marrali M, Fernández-Iglesias A, Hall A, Luong TV, Viollet B, Pinzani M, Rombouts K. Marrone G, et al. Among authors: mazza g. Hepatology. 2018 Sep;68(3):1140-1153. doi: 10.1002/hep.30029. Epub 2018 Jul 16. Hepatology. 2018. PMID: 29663481
Hepatic regenerative medicine.
Mazza G, De Coppi P, Gissen P, Pinzani M. Mazza G, et al. J Hepatol. 2015 Aug;63(2):523-4. doi: 10.1016/j.jhep.2015.05.001. Epub 2015 Jun 10. J Hepatol. 2015. PMID: 26070391 Free article. No abstract available.
Engineering in vitro models of hepatofibrogenesis.
Mazza G, Al-Akkad W, Rombouts K. Mazza G, et al. Adv Drug Deliv Rev. 2017 Nov 1;121:147-157. doi: 10.1016/j.addr.2017.05.018. Epub 2017 May 31. Adv Drug Deliv Rev. 2017. PMID: 28578016 Review.
Cirrhotic Human Liver Extracellular Matrix 3D Scaffolds Promote Smad-Dependent TGF-β1 Epithelial Mesenchymal Transition.
Mazza G, Telese A, Al-Akkad W, Frenguelli L, Levi A, Marrali M, Longato L, Thanapirom K, Vilia MG, Lombardi B, Crowley C, Crawford M, Karsdal MA, Leeming DJ, Marrone G, Bottcher K, Robinson B, Del Rio Hernandez A, Tamburrino D, Spoletini G, Malago M, Hall AR, Godovac-Zimmermann J, Luong TV, De Coppi P, Pinzani M, Rombouts K. Mazza G, et al. Cells. 2019 Dec 28;9(1):83. doi: 10.3390/cells9010083. Cells. 2019. PMID: 31905709 Free PMC article.
AICAR and compound C negatively modulate HCC-induced primary human hepatic stellate cell activation in vitro.
Böttcher K, Longato L, Marrone G, Mazza G, Ghemtio L, Hall A, Luong TV, Caruso S, Viollet B, Zucman-Rossi J, Pinzani M, Rombouts K. Böttcher K, et al. Among authors: mazza g. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G543-G556. doi: 10.1152/ajpgi.00262.2020. Epub 2021 Jan 6. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33406006 Free article.
Decellularized Human Gut as a Natural 3D Platform for Research in Intestinal Fibrosis.
Giuffrida P, Curti M, Al-Akkad W, Biel C, Crowley C, Frenguelli L, Telese A, Hall A, Tamburrino D, Spoletini G, Fusai G, Tinozzi FP, Pietrabissa A, Corazza GR, De Coppi P, Pinzani M, Di Sabatino A, Rombouts K, Mazza G. Giuffrida P, et al. Among authors: mazza g. Inflamm Bowel Dis. 2019 Oct 18;25(11):1740-1750. doi: 10.1093/ibd/izz115. Inflamm Bowel Dis. 2019. PMID: 31199863
Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance.
Al-Akkad W, Acedo P, Vilia MG, Frenguelli L, Ney A, Rodriguez-Hernandez I, Labib PL, Tamburrino D, Spoletini G, Hall AR, Canestrari S, Osnato A, Garcia-Bernardo J, Sejour L, Vassileva V, Vlachos IS, Fusai G, Luong TV, Whittaker SR, Pereira SP, Vallier L, Pinzani M, Rombouts K, Mazza G. Al-Akkad W, et al. Among authors: mazza g. Cells. 2022 Nov 17;11(22):3652. doi: 10.3390/cells11223652. Cells. 2022. PMID: 36429078 Free PMC article.
458 results