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Inhibitors of Apoptosis Protein Antagonists (Smac Mimetic Compounds) Control Polarization of Macrophages during Microbial Challenge and Sterile Inflammatory Responses.
Front Immunol. 2018 Jan 9;8:1792. doi: 10.3389/fimmu.2017.01792. eCollection 2017.
Front Immunol. 2018.
PMID: 29375545
Free PMC article.
Low doses of gamma irradiation potentially modifies immunosuppressive tumor microenvironment by retuning tumor-associated macrophages: lesson from insulinoma.
Prakash H, Klug F, Nadella V, Mazumdar V, Schmitz-Winnenthal H, Umansky L.
Prakash H, et al.
Carcinogenesis. 2016 Mar;37(3):301-313. doi: 10.1093/carcin/bgw007. Epub 2016 Jan 19.
Carcinogenesis. 2016.
PMID: 26785731
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Brucella targets the host ubiquitin-specific protease, Usp8, through the effector protein, TcpB, for facilitating infection of macrophages.
Joshi K, Mazumdar V, Nandi BR, Radhakrishnan GK.
Joshi K, et al.
Infect Immun. 2024 Feb 13;92(2):e0028923. doi: 10.1128/iai.00289-23. Epub 2024 Jan 4.
Infect Immun. 2024.
PMID: 38174929
Free PMC article.
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Immuno-profiling of Brucella proteins for developing improved vaccines and DIVA capable serodiagnostic assays for brucellosis.
Nandini P, Jakka P, Murugan S, Mazumdar V, Kumar D, Prakash R, Barbuddhe SB, Radhakrishnan G.
Nandini P, et al.
Front Microbiol. 2023 Oct 4;14:1253349. doi: 10.3389/fmicb.2023.1253349. eCollection 2023.
Front Microbiol. 2023.
PMID: 37860136
Free PMC article.
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Host F-Box Protein 22 Enhances the Uptake of Brucella by Macrophages and Drives a Sustained Release of Proinflammatory Cytokines through Degradation of the Anti-Inflammatory Effector Proteins of Brucella.
Mazumdar V, Joshi K, Nandi BR, Namani S, Gupta VK, Radhakrishnan G.
Mazumdar V, et al.
Infect Immun. 2022 May 19;90(5):e0006022. doi: 10.1128/iai.00060-22. Epub 2022 Apr 14.
Infect Immun. 2022.
PMID: 35420446
Free PMC article.
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Outer membrane protein 25 of Brucella suppresses TLR-mediated expression of proinflammatory cytokines through degradation of TLRs and adaptor proteins.
Murugan S, Nandi BR, Mazumdar V, Joshi K, Nandini P, Namani S, Jakka P, Radhakrishnan GK.
Murugan S, et al.
J Biol Chem. 2023 Nov;299(11):105309. doi: 10.1016/j.jbc.2023.105309. Epub 2023 Sep 29.
J Biol Chem. 2023.
PMID: 37778729
Free PMC article.
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