Mayne CG - Search Results

1

Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance.

Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Katzenellenbogen JA, et al. Among authors: mayne cg. Nat Rev Cancer. 2018 Jun;18(6):377-388. doi: 10.1038/s41568-018-0001-z. Nat Rev Cancer. 2018. PMID: 29662238 Free PMC article. Review.

2

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.

Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Fanning SW, et al. Among authors: mayne cg. Elife. 2016 Feb 2;5:e12792. doi: 10.7554/eLife.12792. Elife. 2016. PMID: 26836308 Free PMC article.

3

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.

Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, Hosfield DJ, Chandarlapaty S, Tajkhorshid E, Nettles KW, Griffin PR, Shen Y, Katzenellenbogen JA, Brown M, Greene GL. Fanning SW, et al. Among authors: mayne cg. Elife. 2018 Nov 29;7:e37161. doi: 10.7554/eLife.37161. Elife. 2018. PMID: 30489256 Free PMC article.

4

Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance.

Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Katzenellenbogen JA, et al. Among authors: mayne cg. Nat Rev Cancer. 2018 Oct;18(10):662. doi: 10.1038/s41568-018-0053-0. Nat Rev Cancer. 2018. PMID: 30185950

5

Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.

Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Sharma A, et al. Among authors: mayne cg. ACS Chem Biol. 2018 Dec 21;13(12):3374-3384. doi: 10.1021/acschembio.8b00877. Epub 2018 Nov 26. ACS Chem Biol. 2018. PMID: 30404440 Free PMC article.

6

Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer.

Mayne CG, Toy W, Carlson KE, Bhatt T, Fanning SW, Greene GL, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA, Tajkhorshid E. Mayne CG, et al. Mol Cancer Res. 2021 Sep;19(9):1559-1570. doi: 10.1158/1541-7786.MCR-20-1017. Epub 2021 May 21. Mol Cancer Res. 2021. PMID: 34021071 Free PMC article.

7

Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs).

Moore TW, Mayne CG, Katzenellenbogen JA. Moore TW, et al. Among authors: mayne cg. Mol Endocrinol. 2010 Apr;24(4):683-95. doi: 10.1210/me.2009-0362. Epub 2009 Nov 20. Mol Endocrinol. 2010. PMID: 19933380 Free PMC article. Review.

8

A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment.

Li Y, Coons LA, Houtman R, Carlson KE, Martin TA, Mayne CG, Melchers D, Jefferson TB, Ramsey JT, Katzenellenbogen JA, Korach KS. Li Y, et al. Among authors: mayne cg. Sci Signal. 2020 Sep 22;13(650):eaaw4653. doi: 10.1126/scisignal.aaw4653. Sci Signal. 2020. PMID: 32963012 Free PMC article.

9

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues.

Madak-Erdogan Z, Kim SH, Gong P, Zhao YC, Zhang H, Chambliss KL, Carlson KE, Mayne CG, Shaul PW, Korach KS, Katzenellenbogen JA, Katzenellenbogen BS. Madak-Erdogan Z, et al. Among authors: mayne cg. Sci Signal. 2016 May 24;9(429):ra53. doi: 10.1126/scisignal.aad8170. Sci Signal. 2016. PMID: 27221711 Free PMC article.

10

Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget.

Zhou HB, Lee JH, Mayne CG, Carlson KE, Katzenellenbogen JA. Zhou HB, et al. Among authors: mayne cg. J Med Chem. 2010 Apr 22;53(8):3349-60. doi: 10.1021/jm100052k. J Med Chem. 2010. PMID: 20355713 Free PMC article.

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