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Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways.
Chinetti-Gbaguidi G, Baron M, Bouhlel MA, Vanhoutte J, Copin C, Sebti Y, Derudas B, Mayi T, Bories G, Tailleux A, Haulon S, Zawadzki C, Jude B, Staels B. Chinetti-Gbaguidi G, et al. Circ Res. 2011 Apr 15;108(8):985-95. doi: 10.1161/CIRCRESAHA.110.233775. Epub 2011 Feb 24. Circ Res. 2011. PMID: 21350215 Free PMC article.
Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype.
Fuentes L, Wouters K, Hannou SA, Cudejko C, Rigamonti E, Mayi TH, Derudas B, Pattou F, Chinetti-Gbaguidi G, Staels B, Paumelle R. Fuentes L, et al. Among authors: mayi th. Diabetologia. 2011 Dec;54(12):3150-6. doi: 10.1007/s00125-011-2324-0. Epub 2011 Oct 4. Diabetologia. 2011. PMID: 21968977 Free PMC article.
Human adipose tissue macrophages display activation of cancer-related pathways.
Mayi TH, Daoudi M, Derudas B, Gross B, Bories G, Wouters K, Brozek J, Caiazzo R, Raverdi V, Pigeyre M, Allavena P, Mantovani A, Pattou F, Staels B, Chinetti-Gbaguidi G. Mayi TH, et al. J Biol Chem. 2012 Jun 22;287(26):21904-13. doi: 10.1074/jbc.M111.315200. Epub 2012 Apr 17. J Biol Chem. 2012. PMID: 22511784 Free PMC article.
Association between a thyroid hormone receptor-α gene polymorphism and blood pressure but not with coronary heart disease risk.
Goumidi L, Gauthier K, Legry V, Mayi TH, Houzet A, Cottel D, Montaye M, Proust C, Kee F, Ferrières J, Arveiler D, Ducimetière P, Staels B, Dallongeville J, Chinetti G, Flamant F, Amouyel P, Meirhaeghe A. Goumidi L, et al. Among authors: mayi th. Am J Hypertens. 2011 Sep;24(9):1027-34. doi: 10.1038/ajh.2011.94. Epub 2011 Jun 9. Am J Hypertens. 2011. PMID: 21654857