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The inhibition of YAP Signaling Prevents Chronic Biliary Fibrosis in the Abcb4-/- Model by Modulation of Hepatic Stellate Cell and Bile Duct Epithelium Cell Pathophysiology.
Ye L, Ziesch A, Schneider JS, Ofner A, Nieß H, Denk G, Hohenester S, Mayr D, Mahajan UM, Munker S, Khaled NB, Wimmer R, Gerbes AL, Mayerle J, He Y, Geier A, Toni EN, Zhang C, Reiter FP. Ye L, et al. Among authors: mayerle j. Aging Dis. 2024 Feb 1;15(1):338-356. doi: 10.14336/AD.2023.0602. Aging Dis. 2024. PMID: 37307826 Free PMC article.
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Griger J, Widholz SA, Jesinghaus M, de Andrade Krätzig N, Lange S, Engleitner T, Montero JJ, Zhigalova E, Öllinger R, Suresh V, Winkler W, Lier S, Baranov O, Trozzo R, Ben Khaled N, Chakraborty S, Yu J, Konukiewitz B, Steiger K, Pfarr N, Rajput A, Sailer D, Keller G, Schirmacher P, Röcken C, Fagerstedt KW, Mayerle J, Schmidt-Supprian M, Schneider G, Weichert W, Calado DP, Sommermann T, Klöppel G, Rajewsky K, Saur D, Rad R. Griger J, et al. Among authors: mayerle j. Cancer Cell. 2023 Jul 10;41(7):1327-1344.e10. doi: 10.1016/j.ccell.2023.06.001. Epub 2023 Jun 22. Cancer Cell. 2023. PMID: 37352862
In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution.
Fischer A, Lersch R, de Andrade Krätzig N, Strong A, Friedrich MJ, Weber J, Engleitner T, Öllinger R, Yen HY, Kohlhofer U, Gonzalez-Menendez I, Sailer D, Kogan L, Lahnalampi M, Laukkanen S, Kaltenbacher T, Klement C, Rezaei M, Ammon T, Montero JJ, Schneider G, Mayerle J, Heikenwälder M, Schmidt-Supprian M, Quintanilla-Martinez L, Steiger K, Liu P, Cadiñanos J, Vassiliou GS, Saur D, Lohi O, Heinäniemi M, Conte N, Bradley A, Rad L, Rad R. Fischer A, et al. Among authors: mayerle j. Cell Genom. 2023 Mar 8;3(3):100276. doi: 10.1016/j.xgen.2023.100276. eCollection 2023 Mar 8. Cell Genom. 2023. PMID: 36950387 Free PMC article.
Severity of gallstone, sludge or microlithiasis induced pancreatitis - all of the same?
Sirtl S, Bretthauer K, Ahmad M, Hohmann E, Schmidt VF, Allawadhi P, Vornhülz M, Klauss S, Goni E, Vielhauer J, Orgler E, Saka D, Knoblauch M, Hofmann FO, Schirra J, Schulz C, Beyer G, Mahajan UM, Mayerle J, Zorniak M. Sirtl S, et al. Among authors: mayerle j. Pancreas. 2024 May 1. doi: 10.1097/MPA.0000000000002349. Online ahead of print. Pancreas. 2024. PMID: 38696426
Changes over time in the course of advanced pancreatic cancer treatment with systemic chemotherapy: a pooled analysis of five clinical trials from two decades of the German AIO study group.
Weiss L, Fischer LE, Heinemann V, Gieseler F, Hoehler T, Mayerle J, Quietzsch D, Reinacher-Schick A, Schenk M, Seipelt G, Siveke JT, Stahl M, Kaiser U, Waldschmidt DT, Dorman K, Zhang D, Westphalen CB, Boeck S, Haas M. Weiss L, et al. Among authors: mayerle j. ESMO Open. 2024 Apr;9(4):102944. doi: 10.1016/j.esmoop.2024.102944. Epub 2024 Mar 18. ESMO Open. 2024. PMID: 38503144 Free PMC article.
[Acute pancreatitis - diagnosis and management].
Sirtl S, Orgler E, Vielhauer J, Beyer G, Mayerle J. Sirtl S, et al. Among authors: mayerle j. MMW Fortschr Med. 2023 Nov;165(19):52-57. doi: 10.1007/s15006-023-3007-8. MMW Fortschr Med. 2023. PMID: 37919589 German. No abstract available.
Machine learning-based decision tool for selecting patients with idiopathic acute pancreatitis for endosonography to exclude a biliary aetiology.
Sirtl S, Żorniak M, Hohmann E, Beyer G, Dibos M, Wandel A, Phillip V, Ammer-Herrmenau C, Neesse A, Schulz C, Schirra J, Mayerle J, Mahajan UM. Sirtl S, et al. Among authors: mayerle j. World J Gastroenterol. 2023 Sep 21;29(35):5138-5153. doi: 10.3748/wjg.v29.i35.5138. World J Gastroenterol. 2023. PMID: 37744295 Free PMC article.
Three-month life expectancy as inclusion criterion for clinical trials in advanced pancreatic cancer: is it really a valid tool for patient selection?
Weiss L, Heinemann V, Fischer LE, Gieseler F, Hoehler T, Mayerle J, Quietzsch D, Reinacher-Schick A, Schenk M, Seipelt G, Siveke JT, Stahl M, Vehling-Kaiser U, Waldschmidt DT, Dorman K, Zhang D, Westphalen CB, von Bergwelt-Baildon M, Boeck S, Haas M. Weiss L, et al. Among authors: mayerle j. Clin Transl Oncol. 2024 May;26(5):1268-1272. doi: 10.1007/s12094-023-03323-1. Epub 2023 Oct 4. Clin Transl Oncol. 2024. PMID: 37794220 Free PMC article.
390 results